Warner Greene, MD, PhD

Professor

Warner C. Greene, MD, PhD is Director of the Gladstone Center for HIV Cure Research, Senior Investigator, and Nick and Sue Hellmann Distinguished Professor of Translational Medicine at the Gladstone Institute of Virology and Immunology (GIVI). He is the Founding and Emeritus Director of GIVI. Dr. Greene is also Professor of Medicine, Microbiology and of Immunology at UCSF. Dr. Greene is a member of the Institute of Medicine of the National Academies and a fellow of the American Academy for the Advancement of Science. He also serves as Co-Director of the UCSF-Gladstone Center for AIDS Research, and has served as a Councilor and President of the Association of American Physicians. Dr. Greene earned a bachelor’s degree at Stanford University and an MD/PhD at Washington University School of Medicine. He took his internship and residency training in Medicine at the Massachusetts General Hospital at Harvard. After serving as a Senior Investigator at the National Cancer Institute and a Professor of Medicine and Howard Hughes Investigator at Duke University Medical Center, Dr. Greene accepted his current position as the Founding Director of the Gladstone Institute of Virology and Immunology in 1991. The ongoing research in Dr. Greene’s laboratory focuses on the molecular mechanisms underlying HIV pathogenesis, latency, and transmission. He is the author of more than 380 scientific papers and has been recognized as one of the 100 Most Cited Scientists in the world. In 2007, Dr. Greene expanded his work to include global health in sub-Saharan Africa in his service as president and executive chairman of the Accordia Global Health Foundation. Accordia established the Infectious Diseases Institute at Makerere University in Uganda, which has trained thousands of African health care workers, is caring for 30,000 HIV-infected patients, and has brought health care to nearly 500,000 people living in remote rural regions of Uganda. In 2016, Accordia merged with Africare.

Education

1979 - Internal Medicine Residency, Massachusetts General Hospital

1978 - Internal Medicine Internship, Massachusetts General Hospital

MD, PhD, 1977 - Medical Scientist Training Program, Washington University School of Medicine

BA, 1971 - , Stanford University

Honors and Awards

Lifetime Achievement Award for Scientific Contributions, Institute of Human Virology, 2019
• Honorary Doctoral Degree and Commencement Speaker, Drexel University, 2015
Elected as Member, American Academy of Arts & Sciences, 2014
Francis Gilman Blake Award, Association of American Physicians, 2013
President, Association of American Physicians, 2012-2013
Distinguished Research Career Award, Ohio State University Center for Retrovirus Research, 2012
Alumni Achievement Award, Washington University in St. Louis, 2012
Center Director, Global Virus Network, 2011-pres
President-Elect, Association of American Physicians, 2011-2012
Councilor, Association of American Physicians, 2005-2011
Elected as Member, National Academy of Medicine, 2005
Elected Fellow, American Association for the Advancement of Science, 2004
Honorary Co-Chair, AIDS Memorial Advisory Board, 2003-pres
Board of Directors, Academic Alliance Foundation, 2003-pres
Selected as Original Member, ISI Highly Cited Researchers, 2001
Executive Committee and Chair of Scientific Committee, Waterford Project, 2000
Institutional Representative, American Society for Clinical Investigation, 1998-2001
Member, Mayor's AIDS Scientific Advisory Council, 1997-1998
Co-Chair, Keystone AIDS Symposium, 1995
Co-Chair, Scientific Committee, 1st-3rd National Conferences on Human Retroviruses & Related Infections, 1994-1996
Vice President, American Society for Clinical Investigation, 1993-1994
Elected, California Academy of Medicine, 1993
Elected, Association of American Physicians, 1990
Recipient, Young Investigator Award, American Rheumatism Association, 1988
Recipient, Outstanding Investigator Award, American Federation for Clinical Research, 1987
Elected, American Society for Clinical Investigation, 1985
Recipient, Award in the Biological Sciences, Washington Academy of Sciences, 1984
100 Most Cited Scientists, Institute for Scientific Information (Science Citation Index), 1981-1988
Elected Member, Alpha Omega Alpha, 1977
Prize in Medicine, St. Louis Internists, 1977
Research Honorary, Sigma Xi, 1976
Honors Program in Biology, Stanford University, 1970-1971
Recipient, Research Fellowship Award, California Heart Association, 1970

Publications

Li Z, Deeks SG, Ott M, Greene WC. Comprehensive synergy mapping links a BAF- and NSL-containing "supercomplex" to the transcriptional silencing of HIV-1. Cell reports 2023. PMID: 37682714
Kong W, Montano M, Corley MJ, Helmy E, Kobayashi H, Kinisu M, Suryawanshi R, Luo X, Royer LA, Roan NR, Ott M, Ndhlovu LC, Greene WC. Neuropilin-1 Mediates SARS-CoV-2 Infection of Astrocytes in Brain Organoids, Inducing Inflammation Leading to Dysfunction and Death of Neurons. mBio 2022. PMID: 36314791
Montano M, Victor AR, Griffin DK, Duong T, Bolduc N, Farmer A, Garg V, Hadjantonakis AK, Coates A, Barnes FL, Zouves CG, Greene WC, Viotti M. SARS-CoV-2 can infect human embryos. Scientific Reports 2022. PMID: 36104397
Packard TA, Schwarzer R, Herzig E, Rao D, Luo X, Egedal JH, Hsiao F, Widera M, Hultquist JF, Grimmett ZW, Messer RJ, Krogan NJ, Deeks SG, Roan NR, Dittmer U, Hasenkrug KJ, Greene WC. CCL2: a Chemokine Potentially Promoting Early Seeding of the Latent HIV Reservoir. mBio 2022. PMID: 36073812
George AF, McGregor M, Gingrich D, Neidleman J, Marquez RS, Young KC, Thanigaivelan KL, Greene WC, Tien PC, Deitchman AN, Spitzer TL, Roan NR. Female Genital Fibroblasts Diminish the In Vitro Efficacy of PrEP against HIV. Viruses 2022. PMID: 36016345
Nakanjako D, Castelnuovo B, Sewankambo N, Kakaire T, Brough RL, Katabira ET, Thomas DL, Quinn TC, Colebunders R, Greene WC, Ronald AR, Coutinho A, McAdam K, Serwadda D, Wabwire-Mangen F, Katongole-Mbidde E, Musoke P, Joloba M, McKinnell H, Kamya M, Mayanja-Kizza H, Manabe YC, Kambugu A. Infectious Diseases Institute at Makerere University College of Health Sciences: a case study of a sustainable capacity building model for health care, research and training. African health sciences 2022. PMID: 36321127
Prahl M, Golan Y, Cassidy AG, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin CY, Gonzalez VJ, Chidboy MA, Warrier L, Buarpung S, Murtha AP, Flaherman VJ, Greene WC, Wu AHB, Lynch KL, Rajan J, Gaw SL. Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and infancy. Nature communications 2022. PMID: 35908075
Matsui Y, Li L, Prahl M, Cassidy AG, Ozarslan N, Golan Y, Gonzalez VJ, Lin CY, Jigmeddagva U, Chidboy MA, Montano M, Taha TY, Khalid MM, Sreekumar B, Hayashi JM, Chen PY, Kumar GR, Warrier L, Wu AH, Song D, Jegatheesan P, Rai DS, Govindaswami B, Needens JM, Rincon M, Myatt L, Asiodu IV, Flaherman VJ, Afshar Y, Jacoby VL, Murtha AP, Robinson JF, Ott M, Greene WC, Gaw SL. Neutralizing antibody activity against SARS-CoV-2 variants in gestational age-matched mother-infant dyads after infection or vaccination. "HIV within the House Ball Community and the Promise of Community-based Social Structures for Intervention and Support" 2022. PMID: 35579965
Luo X, Frouard J, Zhang G, Neidleman J, Xie G, Sheedy E, Roan NR, Greene WC. Subsets of Tissue CD4 T Cells Display Different Susceptibilities to HIV Infection and Death: Analysis by CyTOF and Single Cell RNA-seq. Frontiers in immunology 2022. PMID: 35784348
Suryawanshi RK, Chen IP, Ma T, Syed AM, Brazer N, Saldhi P, Simoneau CR, Ciling A, Khalid MM, Sreekumar B, Chen PY, Kumar GR, Montano M, Gascon R, Tsou CL, Garcia-Knight MA, Sotomayor-Gonzalez A, Servellita V, Gliwa A, Nguyen J, Silva I, Milbes B, Kojima N, Hess V, Shacreaw M, Lopez L, Brobeck M, Turner F, Soveg FW, George AF, Fang X, Maishan M, Matthay M, Morris MK, Wadford D, Hanson C, Greene WC, Andino R, Spraggon L, Roan NR, Chiu CY, Doudna JA, Ott M. Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination. "HIV within the House Ball Community and the Promise of Community-based Social Structures for Intervention and Support" 2022. PMID: 35584773
Suryawanshi RK, Chen IP, Ma T, Syed AM, Simoneau CR, Ciling A, Khalid MM, Sreekumar B, Chen PY, George AF, Kumar GR, Montano M, Garcia-Knight MA, Brazer N, Saldhi P, Sotomayor-Gonzalez A, Servellita V, Gliwa A, Nguyen J, Silva I, Milbes B, Kojima N, Hess V, Shacreaw M, Lopez L, Brobeck M, Turner F, Soveg FW, Fang X, Maishan M, Matthay M, Morris MK, Wadford D, Hanson C, Greene WC, Andino R, Spraggon L, Roan NR, Chiu CY, Doudna J, Ott M. Limited cross-variant immunity after infection with the SARS-CoV-2 Omicron variant without vaccination. "HIV within the House Ball Community and the Promise of Community-based Social Structures for Intervention and Support" 2022. PMID: 35075459
George AF, Luo X, Neidleman J, Hoh R, Vohra P, Thomas R, Shin MG, Lee MJ, Blish CA, Deeks SG, Greene WC, Lee SA, Roan NR. Deep Phenotypic Analysis of Blood and Lymphoid T and NK Cells From HIV+ Controllers and ART-Suppressed Individuals. "HIV within the House Ball Community and the Promise of Community-based Social Structures for Intervention and Support" 2022. PMID: 35154118
Prahl M, Golan Y, Cassidy A, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin C, Gonzalez V, Chidboy M, Warrier L, Buarpung S, Murtha A, Flaherman V, Greene W, Wu A, Lynch K, Rajan J, Gaw S. Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and early infancy. Research square 2021. PMID: 34931183
Prahl M, Golan Y, Cassidy AG, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin CY, Gonzalez VJ, Chidboy MA, Warrier L, Buarpung S, Murtha AP, Flaherman VJ, Greene WC, Wu AHB, Lynch KL, Rajan J, Gaw SL. Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and early infancy. "HIV within the House Ball Community and the Promise of Community-based Social Structures for Intervention and Support" 2021. PMID: 34931197
Pedersen JG, Egedal JH, Packard TA, Thavachelvam K, Xie G, van der Sluis RM, Greene WC, Roan NR, Jakobsen MR. Cell-Extrinsic Priming Increases Permissiveness of CD4+ T Cells to Human Immunodeficiency Virus Infection by Increasing C-C Chemokine Receptor Type 5 Co-receptor Expression and Cellular Activation Status. "HIV within the House Ball Community and the Promise of Community-based Social Structures for Intervention and Support" 2021. PMID: 34899645
Ryu JK, Sozmen EG, Dixit K, Montano M, Matsui Y, Liu Y, Helmy E, Deerinck TJ, Yan Z, Schuck R, Acevedo RM, Spencer CM, Thomas R, Pico AR, Zamvil SS, Lynch KL, Ellisman MH, Greene WC, Akassoglou K. SARS-CoV-2 spike protein induces abnormal inflammatory blood clots neutralized by fibrin immunotherapy. "HIV within the House Ball Community and the Promise of Community-based Social Structures for Intervention and Support" 2021. PMID: 34671772
Neidleman J, Luo X, McGregor M, Xie G, Murray V, Greene WC, Lee SA, Roan NR. mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior infection status. eLife 2021. PMID: 34636722
Luo X, Mouquet H, Schwartz O, Greene WC. Bystander CD4 T-cell death is inhibited by broadly neutralizing anti-HIV antibodies only at levels blocking cell-to-cell viral transmission. The Journal of biological chemistry 2021. PMID: 34418431
Neidleman J, Luo X, McGregor M, Xie G, Murray V, Greene WC, Lee SA, Roan NR. mRNA vaccine-induced SARS-CoV-2-specific T cells recognize B.1.1.7 and B.1.351 variants but differ in longevity and homing properties depending on prior infection status. bioRxiv : the preprint server for biology 2021. PMID: 34013277
Neidleman J, Luo X, George AF, McGregor M, Yang J, Yun C, Murray V, Gill G, Greene WC, Vasquez J, Lee SA, Ghosn E, Lynch KL, Roan NR. Distinctive features of SARS-CoV-2-specific T cells predict recovery from severe COVID-19. Cell reports 2021. PMID: 34260965
Egedal JH, Xie G, Packard TA, Laustsen A, Neidleman J, Georgiou K, Pillai SK, Greene WC, Jakobsen MR, Roan NR. Hyaluronic acid is a negative regulator of mucosal fibroblast-mediated enhancement of HIV infection. Mucosal immunology 2021. PMID: 33976386
Xie G, Luo X, Ma T, Frouard J, Neidleman J, Hoh R, Deeks SG, Greene WC, Roan NR. Characterization of HIV-induced remodeling reveals differences in infection susceptibility of memory CD4+ T cell subsets in vivo. Cell reports 2021. PMID: 33910003
Neidleman J, Luo X, George AF, McGregor M, Yang J, Yun C, Murray V, Gill G, Greene WC, Vasquez J, Lee S, Ghosn E, Lynch K, Roan NR. Distinctive features of SARS-CoV-2-specific T cells predict recovery from severe COVID-19. medRxiv : the preprint server for health sciences 2021. PMID: 33532792
Gramatica A, Schwarzer R, Brantley W, Varco-Merth B, Sperber HS, Hull PA, Montano M, Migueles SA, Rosenthal D, Hogan LE, Johnson JR, Packard TA, Grimmett ZW, Herzig E, Besnard E, Nekorchuk M, Hsiao F, Deeks SG, Snape M, Kiernan B, Roan NR, Lifson JD, Estes JD, Picker LJ, Verdin E, Krogan NJ, Henrich TJ, Connors M, Ott M, Pillai SK, Okoye AA, Greene WC. Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity Ex Vivo and In Vivo. Journal of virology 2021. PMID: 33536176
Li Z, Hajian C, Greene WC. Identification of unrecognized host factors promoting HIV-1 latency. PLoS pathogens 2020. PMID: 33270809
Moron-Lopez S, Telwatte S, Sarabia I, Battivelli E, Montano M, Macedo AB, Aran D, Butte AJ, Jones RB, Bosque A, Verdin E, Greene WC, Wong JK, Yukl SA. Human splice factors contribute to latent HIV infection in primary cell models and blood CD4+ T cells from ART-treated individuals. PLoS pathogens 2020. PMID: 33253324
Neidleman J, Luo X, Frouard J, Xie G, Hsiao F, Ma T, Morcilla V, Lee A, Telwatte S, Thomas R, Tamaki W, Wheeler B, Hoh R, Somsouk M, Vohra P, Milush J, James KS, Archin NM, Hunt PW, Deeks SG, Yukl SA, Palmer S, Greene WC, Roan NR. Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir. eLife 2020. PMID: 32990219
Neidleman J, Luo X, Frouard J, Xie G, Gill G, Stein ES, McGregor M, Ma T, George AF, Kosters A, Greene WC, Vasquez J, Ghosn E, Lee S, Roan NR. SARS-CoV-2-specific T cells exhibit phenotypic features of robust helper function, lack of terminal differentiation, and high proliferative potential. Cell reports. Medicine 2020. PMID: 32839763
Neidleman J, Luo X, Frouard J, Xie G, Gurjot G, Stein ES, McGregor M, Ma T, George AF, Kosters A, Greene WC, Vasquez J, Ghosn E, Lee S, Roan NR. SARS-CoV-2-specific T cells exhibit unique features characterized by robust helper function, lack of terminal differentiation, and high proliferative potential. bioRxiv : the preprint server for biology 2020. PMID: 32577663
Ma T, Luo X, George AF, Mukherjee G, Sen N, Spitzer TL, Giudice LC, Greene WC, Roan NR. HIV efficiently infects T cells from the endometrium and remodels them to promote systemic viral spread. eLife 2020. PMID: 32452381
Hsiao F, Frouard J, Gramatica A, Xie G, Telwatte S, Lee GQ, Roychoudhury P, Schwarzer R, Luo X, Yukl SA, Lee S, Hoh R, Deeks SG, Jones RB, Cavrois M, Greene WC, Roan NR. Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection. PLoS pathogens 2020. PMID: 32353080
George AF, Jang KS, Nyegaard M, Neidleman J, Spitzer TL, Xie G, Chen JC, Herzig E, Laustsen A, Marques de Menezes EG, Houshdaran S, Pilcher CD, Norris PJ, Jakobsen MR, Greene WC, Giudice LC, Roan NR. Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-11 signaling. Human reproduction (Oxford, England) 2020. PMID: 32219408
Schwarzer R, Gramatica A, Greene WC. Reduce and Control: A Combinatorial Strategy for Achieving Sustained HIV Remissions in the Absence of Antiretroviral Therapy. Viruses 2020. PMID: 32046251
Luo X, Herzig E, Doitsh G, Grimmett ZW, Muñoz-Arias I, Greene WC. HIV-2 depletes CD4 T cells through pyroptosis despite Vpx-dependent degradation of SAMHD1. Journal of virology 2019. PMID: 31578293
Telwatte S, Morón-López S, Aran D, Kim P, Hsieh C, Joshi S, Montano M, Greene WC, Butte AJ, Wong JK, Yukl SA. Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency. Retrovirology 2019. PMID: 31711503
Herzig E, Kim KC, Packard TA, Vardi N, Schwarzer R, Gramatica A, Deeks SG, Williams SR, Landgraf K, Killeen N, Martin DW, Weinberger LS, Greene WC. Attacking Latent HIV with convertibleCAR-T Cells, a Highly Adaptable Killing Platform. Cell 2019. PMID: 31668804
Mainzer C, Packard T, Bordes S, Closs B, Greene WC, Elias PM, Uchida Y. Tissue microenvironment initiates an immune response to structural components of S. aureus. Experimental dermatology 2018. PMID: 30566255
Pulugulla SH, Packard TA, Galloway NLK, Grimmett ZW, Doitsh G, Adamik J, Galson DL, Greene WC, Auron PE. Distinct mechanisms regulate IL1B gene transcription in lymphoid CD4 T cells and monocytes. Cytokine 2018. PMID: 30300855
Martin JW, Chen JC, Neidleman J, Tatsumi K, Hu J, Giudice LC, Greene WC, Roan NR. Potent and rapid activation of tropomyosin-receptor kinase A in endometrial stromal fibroblasts by seminal plasma. 2018. PMID: 29518187
Battivelli E, Dahabieh MS, Abdel-Mohsen M, Svensson JP, Tojal Da Silva I, Cohn LB, Gramatica A, Deeks S, Greene WC, Pillai SK, Verdin E. Distinct chromatin functional states correlate with HIV latency reactivation in infected primary CD4+ T Cells. 2018. PMID: 29714165
Cavrois M, Banerjee T, Mukherjee G, Raman N, Hussien R, Rodriguez BA, Vasquez J, Spitzer MH, Lazarus NH, Jones JJ, Ochsenbauer C, McCune JM, Butcher EC, Arvin AM, Sen N, Greene WC, Roan NR. Mass Cytometric Analysis of HIV Entry, Replication, and Remodeling in Tissue CD4+ T Cells. Volume 20 of Issue 4. 2017. PMID: 28746881
Roan NR, Sandi-Monroy N, Kohgadai N, Usmani SM, Hamil KG, Neidleman J, Montano M, Ständker L, Röcker A, Cavrois M, Rosen J, Marson K, Smith JF, Pilcher CD, Gagsteiger F, Sakk O, O'Rand M, Lishko PV, Kirchhoff F, Münch J, Greene WC. Semen amyloids participate in spermatozoa selection and clearance. Volume 6. 2017. PMID: 28653619
Boehm D, Jeng M, Camus G, Gramatica A, Schwarzer R, Johnson JR, Hull PA, Montano M, Sakane N, Pagans S, Godin R, Deeks SG, Krogan NJ, Greene WC, Ott M. SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency. Volume 21 of Issue 5. 2017. PMID: 28494238
Doitsh G, Galloway NL, Geng X, Yang Z, Monroe KM, Zepeda O, Hunt PW, Hatano H, Sowinski S, Muñoz-Arias I, Greene WC. Corrigendum: Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection. Volume 544 of Issue 7648. 2017. PMID: 28329768
Neidleman JA, Chen JC, Kohgadai N, Müller JA, Laustsen A, Thavachelvam K, Jang KS, Stürzel CM, Jones JJ, Ochsenbauer C, Chitre A, Somsouk M, Garcia MM, Smith JF, Greenblatt RM, Münch J, Jakobsen MR, Giudice LC, Greene WC, Roan NR. Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells. Volume 13 of Issue 2. PLoS pathogens 2017. PMID: 28207890
Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, Krogan NJ, Siliciano RF, Weissman JS, Verdin E. The mTOR Complex Controls HIV Latency. Volume 20 of Issue 6. 2016. PMID: 27978436
Li P, Kaiser P, Lampiris HW, Kim P, Yukl SA, Havlir DV, Greene WC, Wong JK. Stimulating the RIG-I pathway to kill cells in the latent HIV reservoir following viral reactivation. Volume 22 of Issue 7. Nature medicine 2016. PMID: 27294875
LoRicco JG, Xu CS, Neidleman J, Bergkvist M, Greene WC, Roan NR, Makhatadze GI. Gallic Acid Is an Antagonist of Semen Amyloid Fibrils That Enhance HIV-1 Infection. Volume 291 of Issue 27. The Journal of biological chemistry 2016. PMID: 27226574
Doitsh G, Greene WC. Dissecting How CD4 T Cells Are Lost During HIV Infection. Volume 19 of Issue 3. 2016. PMID: 26962940
Muñoz-Arias I, Doitsh G, Yang Z, Sowinski S, Ruelas D, Greene WC. Blood-Derived CD4 T Cells Naturally Resist Pyroptosis during Abortive HIV-1 Infection. Volume 18 of Issue 4. 2015. PMID: 26468749
Galloway NL, Doitsh G, Monroe KM, Yang Z, Muñoz-Arias I, Levy DN, Greene WC. Cell-to-Cell Transmission of HIV-1 Is Required to Trigger Pyroptotic Death of Lymphoid-Tissue-Derived CD4 T Cells. Volume 12 of Issue 10. 2015. PMID: 26321639
Ruelas DS, Chan JK, Oh E, Heidersbach AJ, Hebbeler AM, Chavez L, Verdin E, Rape M, Greene WC. MicroRNA-155 Reinforces HIV Latency. Volume 290 of Issue 22. The Journal of biological chemistry 2015. PMID: 25873391
Zirafi O, Kim KA, Roan NR, Kluge SF, Müller JA, Jiang S, Mayer B, Greene WC, Kirchhoff F, Münch J. Semen enhances HIV infectivity and impairs the antiviral efficacy of microbicides. Volume 6 of Issue 262. Science translational medicine 2014. PMID: 25391483
Cavrois M, Neidleman J, Greene WC. HIV-1 Fusion Assay. Volume 4 of Issue 16. 2014. PMID: 27525294
Yang Z, Greene WC. A new activity for SAMHD1 in HIV restriction. Volume 20 of Issue 8. Nature medicine 2014. PMID: 25100520
Roan NR, Liu H, Usmani SM, Neidleman J, Müller JA, Avila-Herrera A, Gawanbacht A, Zirafi O, Chu S, Dong M, Kumar ST, Smith JF, Pollard KS, Fändrich M, Kirchhoff F, Münch J, Witkowska HE, Greene WC. Liquefaction of semen generates and later degrades a conserved semenogelin peptide that enhances HIV infection. Volume 88 of Issue 13. Journal of virology 2014. PMID: 24741080
Roan NR, Chu S, Liu H, Neidleman J, Witkowska HE, Greene WC. Interaction of fibronectin with semen amyloids synergistically enhances HIV infection. Volume 210 of Issue 7. The Journal of infectious diseases 2014. PMID: 24719472
Usmani SM, Zirafi O, Müller JA, Sandi-Monroy NL, Yadav JK, Meier C, Weil T, Roan NR, Greene WC, Walther P, Nilsson KP, Hammarström P, Wetzel R, Pilcher CD, Gagsteiger F, Fändrich M, Kirchhoff F, Münch J. Direct visualization of HIV-enhancing endogenous amyloid fibrils in human semen. Volume 5. 2014. PMID: 24691351
Chen JC, Johnson BA, Erikson DW, Piltonen TT, Barragan F, Chu S, Kohgadai N, Irwin JC, Greene WC, Giudice LC, Roan NR. Seminal plasma induces global transcriptomic changes associated with cell migration, proliferation and viability in endometrial epithelial cells and stromal fibroblasts. Volume 29 of Issue 6. 2014. PMID: 24626806
Doitsh G, Galloway NL, Geng X, Yang Z, Monroe KM, Zepeda O, Hunt PW, Hatano H, Sowinski S, Muñoz-Arias I, Greene WC. Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection. Volume 505 of Issue 7484. 2014. PMID: 24356306
Spina CA, Anderson J, Archin NM, Bosque A, Chan J, Famiglietti M, Greene WC, Kashuba A, Lewin SR, Margolis DM, Mau M, Ruelas D, Saleh S, Shirakawa K, Siliciano RF, Singhania A, Soto PC, Terry VH, Verdin E, Woelk C, Wooden S, Xing S, Planelles V. An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients. Volume 9 of Issue 12. PLoS pathogens 2013. PMID: 24385908
Monroe KM, Yang Z, Johnson JR, Geng X, Doitsh G, Krogan NJ, Greene WC. IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV. Volume 343 of Issue 6169. 2013. PMID: 24356113
Cavrois M, Neidleman J, Santiago ML, Derdeyn CA, Hunter E, Greene WC. Enhanced fusion and virion incorporation for HIV-1 subtype C envelope glycoproteins with compact V1/V2 domains. Volume 88 of Issue 4. Journal of virology 2013. PMID: 24335304
Greene WC. Solutions to global health challenges: no more Band-Aids. Volume 123 of Issue 11. The Journal of clinical investigation 2013. PMID: 24177468
Chan JK, Bhattacharyya D, Lassen KG, Ruelas D, Greene WC. Calcium/calcineurin synergizes with prostratin to promote NF-?B dependent activation of latent HIV. Volume 8 of Issue 10. PloS one 2013. PMID: 24204950
Ruelas DS, Greene WC. An integrated overview of HIV-1 latency. Volume 155 of Issue 3. 2013. PMID: 24243012
Webster B, Ott M, Greene WC. Evasion of superinfection exclusion and elimination of primary viral RNA by an adapted strain of hepatitis C virus. Volume 87 of Issue 24. Journal of virology 2013. PMID: 24089557
Vogt DA, Camus G, Herker E, Webster BR, Tsou CL, Greene WC, Yen TS, Ott M. Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein. Volume 9 of Issue 4. PLoS pathogens 2013. PMID: 23593007
Webster B, Wissing S, Herker E, Ott M, Greene WC. Rapid intracellular competition between hepatitis C viral genomes as a result of mitosis. Volume 87 of Issue 1. Journal of virology 2012. PMID: 23097449
Roan NR, Cavrois M, Greene WC. [Role of semen-derived amyloid fibrils as facilitators of HIV infection]. Volume 28 of Issue 4. 2012. PMID: 22549858
Chan JK, Greene WC. Dynamic roles for NF-?B in HTLV-I and HIV-1 retroviral pathogenesis. Volume 246 of Issue 1. 2012. PMID: 22435562
Pillai SK, Abdel-Mohsen M, Guatelli J, Skasko M, Monto A, Fujimoto K, Yukl S, Greene WC, Kovari H, Rauch A, Fellay J, Battegay M, Hirschel B, Witteck A, Bernasconi E, Ledergerber B, Günthard HF, Wong JK. Role of retroviral restriction factors in the interferon-a-mediated suppression of HIV-1 in vivo. Volume 109 of Issue 8. Proceedings of the National Academy of Sciences of the United States of America 2012. PMID: 22315404
Lassen KG, Hebbeler AM, Bhattacharyya D, Lobritz MA, Greene WC. A flexible model of HIV-1 latency permitting evaluation of many primary CD4 T-cell reservoirs. Volume 7 of Issue 1. PloS one 2012. PMID: 22291913
Tugizov SM, Herrera R, Veluppillai P, Greenspan D, Soros V, Greene WC, Levy JA, Palefsky JM. Differential transmission of HIV traversing fetal oral/intestinal epithelia and adult oral epithelia. Volume 86 of Issue 5. Journal of virology 2011. PMID: 22205732
Roan NR, Müller JA, Liu H, Chu S, Arnold F, Stürzel CM, Walther P, Dong M, Witkowska HE, Kirchhoff F, Münch J, Greene WC. Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection. Volume 10 of Issue 6. 2011. PMID: 22177559
Arnold F, Schnell J, Zirafi O, Stürzel C, Meier C, Weil T, Ständker L, Forssmann WG, Roan NR, Greene WC, Kirchhoff F, Münch J. Naturally occurring fragments from two distinct regions of the prostatic acid phosphatase form amyloidogenic enhancers of HIV infection. Volume 86 of Issue 2. Journal of virology 2011. PMID: 22090109
Wissing S, Muñoz-Lopez M, Macia A, Yang Z, Montano M, Collins W, Garcia-Perez JL, Moran JV, Greene WC. Reprogramming somatic cells into iPS cells activates LINE-1 retroelement mobility. Volume 21 of Issue 1. 2011. PMID: 21989055
Smith DS, Guo K, Barrett BS, Heilman KJ, Evans LH, Hasenkrug KJ, Greene WC, Santiago ML. Noninfectious retrovirus particles drive the APOBEC3/Rfv3 dependent neutralizing antibody response. Volume 7 of Issue 10. PLoS pathogens 2011. PMID: 21998583
Siliciano RF, Greene WC. HIV latency. Volume 1 of Issue 1. 2011. PMID: 22229121
Wissing S, Montano M, Garcia-Perez JL, Moran JV, Greene WC. Endogenous APOBEC3B restricts LINE-1 retrotransposition in transformed cells and human embryonic stem cells. Volume 286 of Issue 42. The Journal of biological chemistry 2011. PMID: 21878639
Sakane N, Kwon HS, Pagans S, Kaehlcke K, Mizusawa Y, Kamada M, Lassen KG, Chan J, Greene WC, Schnoelzer M, Ott M. Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1). Volume 7 of Issue 8. PLoS pathogens 2011. PMID: 21876670
Chan JK, Greene WC. NF-?B/Rel: agonist and antagonist roles in HIV-1 latency. Volume 6 of Issue 1. 2011. PMID: 21242888
Doitsh G, Cavrois M, Lassen KG, Zepeda O, Yang Z, Santiago ML, Hebbeler AM, Greene WC. Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue. Volume 143 of Issue 5. 2010. PMID: 21111238
Tugizov SM, Herrera R, Veluppillai P, Greenspan D, Soros V, Greene WC, Levy JA, Palefsky JM. HIV is inactivated after transepithelial migration via adult oral epithelial cells but not fetal epithelial cells. Volume 409 of Issue 2. 2010. PMID: 21056450
Santiago ML, Smith DS, Barrett BS, Montano M, Benitez RL, Pelanda R, Hasenkrug KJ, Greene WC. Persistent Friend virus replication and disease in Apobec3-deficient mice expressing functional B-cell-activating factor receptor. Volume 85 of Issue 1. Journal of virology 2010. PMID: 20980520
Lassen KG, Wissing S, Lobritz MA, Santiago M, Greene WC. Identification of two APOBEC3F splice variants displaying HIV-1 antiviral activity and contrasting sensitivity to Vif. Volume 285 of Issue 38. The Journal of biological chemistry 2010. PMID: 20624919
Kim KA, Yolamanova M, Zirafi O, Roan NR, Staendker L, Forssmann WG, Burgener A, Dejucq-Rainsford N, Hahn BH, Shaw GM, Greene WC, Kirchhoff F, Münch J. Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI. Volume 7. 2010. PMID: 20573198
Santiago ML, Benitez RL, Montano M, Hasenkrug KJ, Greene WC. Innate retroviral restriction by Apobec3 promotes antibody affinity maturation in vivo. Volume 185 of Issue 2. Journal of immunology (Baltimore, Md. : 1950) 2010. PMID: 20566830
Wissing S, Galloway NL, Greene WC. HIV-1 Vif versus the APOBEC3 cytidine deaminases: an intracellular duel between pathogen and host restriction factors. Volume 31 of Issue 5. 2010. PMID: 20538015
Cavrois M, Neidleman J, Galloway N, Derdeyn CA, Hunter E, Greene WC. Measuring HIV fusion mediated by envelopes from primary viral isolates. Volume 53 of Issue 1. 2010. PMID: 20554044
Roan NR, Sowinski S, Münch J, Kirchhoff F, Greene WC. Aminoquinoline surfen inhibits the action of SEVI (semen-derived enhancer of viral infection). Volume 285 of Issue 3. The Journal of biological chemistry 2009. PMID: 19897482
Chiu YL, Greene WC. APOBEC3G: an intracellular centurion. Volume 364 of Issue 1517. 2009. PMID: 19008196
Richman DD, Margolis DM, Delaney M, Greene WC, Hazuda D, Pomerantz RJ. The challenge of finding a cure for HIV infection. Volume 323 of Issue 5919. 2009. PMID: 19265012
Michel N, Goffinet C, Ganter K, Allespach I, Kewalramani VN, Saifuddin M, Littman DR, Greene WC, Goldsmith MA, Keppler OT. Human cyclin T1 expression ameliorates a T-cell-specific transcriptional limitation for HIV in transgenic rats, but is not sufficient for a spreading infection of prototypic R5 HIV-1 strains ex vivo. Volume 6. 2009. PMID: 19144136
Abbadessa G, Accolla R, Aiuti F, Albini A, Aldovini A, Alfano M, Antonelli G, Bartholomew C, Bentwich Z, Bertazzoni U, Berzofsky JA, Biberfeld P, Boeri E, Buonaguro L, Buonaguro FM, Bukrinsky M, Burny A, Caruso A, Cassol S, Chandra P, Ceccherini-Nelli L, Chieco-Bianchi L, Clerici M, Colombini-Hatch S, de Giuli Morghen C, de Maria A, de Rossi A, Dierich M, Della-Favera R, Dolei A, Douek D, Erfle V, Felber B, Fiorentini S, Franchini G, Gershoni JM, Gotch F, Green P, Greene WC, Hall W, Haseltine W, Jacobson S, Kallings LO, Kalyanaraman VS, Katinger H, Khalili K, Klein G, Klein E, Klotman M, Klotman P, Kotler M, Kurth R, Lafeuillade A, La Placa M, Lewis J, Lillo F, Lisziewicz J, Lomonico A, Lopalco L, Lori F, Lusso P, Macchi B, Malim M, Margolis L, Markham PD, McClure M, Miller N, Mingari MC, Moretta L, Noonan D, O'Brien S, Okamoto T, Pal R, Palese P, Panet A, Pantaleo G, Pavlakis G, Pistello M, Plotkin S, Poli G, Pomerantz R, Radaelli A, Robertguroff M, Roederer M, Sarngadharan MG, Schols D, Secchiero P, Shearer G, Siccardi A, Stevenson M, Svoboda J, Tartaglia J, Torelli G, Tornesello ML, Tschachler E, Vaccarezza M, Vallbracht A, van Lunzen J, Varnier O, Vicenzi E, von Melchner H, Witz I, Zagury D, Zagury JF, Zauli G, Zipeto D. Unsung hero Robert C. Gallo. Volume 323 of Issue 5911. 2009. PMID: 19131607
LaRue RS, Andrésdóttir V, Blanchard Y, Conticello SG, Derse D, Emerman M, Greene WC, Jónsson SR, Landau NR, Löchelt M, Malik HS, Malim MH, Münk C, O'Brien SJ, Pathak VK, Strebel K, Wain-Hobson S, Yu XF, Yuhki N, Harris RS. Guidelines for naming nonprimate APOBEC3 genes and proteins. Volume 83 of Issue 2. Journal of virology 2008. PMID: 18987154
Roan NR, Münch J, Arhel N, Mothes W, Neidleman J, Kobayashi A, Smith-McCune K, Kirchhoff F, Greene WC. The cationic properties of SEVI underlie its ability to enhance human immunodeficiency virus infection. Volume 83 of Issue 1. Journal of virology 2008. PMID: 18945786
Greene WC, Debyser Z, Ikeda Y, Freed EO, Stephens E, Yonemoto W, Buckheit RW, Esté JA, Cihlar T. Novel targets for HIV therapy. Volume 80 of Issue 3. 2008. PMID: 18789977
Santiago ML, Montano M, Benitez R, Messer RJ, Yonemoto W, Chesebro B, Hasenkrug KJ, Greene WC. Apobec3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection. Volume 321 of Issue 5894. 2008. PMID: 18772436
Fauci AS, Johnston MI, Dieffenbach CW, Burton DR, Hammer SM, Hoxie JA, Martin M, Overbaugh J, Watkins DI, Mahmoud A, Greene WC. HIV vaccine research: the way forward. Volume 321 of Issue 5888. 2008. PMID: 18653883
Cavrois M, Neidleman J, Greene WC. The achilles heel of the trojan horse model of HIV-1 trans-infection. Volume 4 of Issue 6. PLoS pathogens 2008. PMID: 18584030
Kwon HS, Brent MM, Getachew R, Jayakumar P, Chen LF, Schnolzer M, McBurney MW, Marmorstein R, Greene WC, Ott M. Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation. Volume 3 of Issue 3. 2008. PMID: 18329615
Chiu YL, Greene WC. The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements. Volume 26. 2008. PMID: 18304004
Roan NR, Greene WC. A seminal finding for understanding HIV transmission. Volume 131 of Issue 6. 2007. PMID: 18083095
Greene WC. A history of AIDS: looking back to see ahead. Volume 37 Suppl 1. 2007. PMID: 17972351
Goffinet C, Michel N, Allespach I, Tervo HM, Hermann V, Kräusslich HG, Greene WC, Keppler OT. Primary T-cells from human CD4/CCR5-transgenic rats support all early steps of HIV-1 replication including integration, but display impaired viral gene expression. Volume 4. 2007. PMID: 17655755
Williams SA, Greene WC. Regulation of HIV-1 latency by T-cell activation. Volume 39 of Issue 1. Cytokine 2007. PMID: 17643313
Ellery PJ, Tippett E, Chiu YL, Paukovics G, Cameron PU, Solomon A, Lewin SR, Gorry PR, Jaworowski A, Greene WC, Sonza S, Crowe SM. The CD16+ monocyte subset is more permissive to infection and preferentially harbors HIV-1 in vivo. Volume 178 of Issue 10. Journal of immunology (Baltimore, Md. : 1950) 2007. PMID: 17475889
Williams SA, Kwon H, Chen LF, Greene WC. Sustained induction of NF-kappa B is required for efficient expression of latent human immunodeficiency virus type 1. Volume 81 of Issue 11. Journal of virology 2007. PMID: 17376917
Soros VB, Greene WC. APOBEC3G and HIV-1: strike and counterstrike. Volume 4 of Issue 1. Current HIV/AIDS reports 2007. PMID: 17338854
Soros VB, Yonemoto W, Greene WC. Newly synthesized APOBEC3G is incorporated into HIV virions, inhibited by HIV RNA, and subsequently activated by RNase H. Volume 3 of Issue 2. PLoS pathogens 2007. PMID: 17291161
Cavrois M, Neidleman J, Kreisberg JF, Greene WC. In vitro derived dendritic cells trans-infect CD4 T cells primarily with surface-bound HIV-1 virions. Volume 3 of Issue 1. PLoS pathogens 2007. PMID: 17238285
Stopak KS, Chiu YL, Kropp J, Grant RM, Greene WC. Distinct patterns of cytokine regulation of APOBEC3G expression and activity in primary lymphocytes, macrophages, and dendritic cells. Volume 282 of Issue 6. The Journal of biological chemistry 2006. PMID: 17110377
Ahuja SK, Aiuti F, Berkhout B, Biberfeld P, Burton DR, Colizzi V, Deeks SG, Desrosiers RC, Dierich MP, Doms RW, Emerman M, Gallo RC, Girard M, Greene WC, Hoxie JA, Hunter E, Klein G, Korber B, Kuritzkes DR, Lederman MM, Malim MH, Marx PA, McCune JM, McMichael A, Miller C, Miller V, Montagnier L, Montefiori DC, Moore JP, Nixon DF, Overbaugh J, Pauza CD, Richman DD, Saag MS, Sattentau Q, Schooley RT, Shattock R, Shaw GM, Stevenson M, Trkola A, Wainberg MA, Weiss RA, Wolinsky S, Zack JA. A plea for justice for jailed medical workers. Volume 314 of Issue 5801. 2006. PMID: 17062652
Chiu YL, Witkowska HE, Hall SC, Santiago M, Soros VB, Esnault C, Heidmann T, Greene WC. High-molecular-mass APOBEC3G complexes restrict Alu retrotransposition. Volume 103 of Issue 42. Proceedings of the National Academy of Sciences of the United States of America 2006. PMID: 17030807
O'Mahony A, Raber J, Montano M, Foehr E, Han V, Lu SM, Kwon H, LeFevour A, Chakraborty-Sett S, Greene WC. NF-kappaB/Rel regulates inhibitory and excitatory neuronal function and synaptic plasticity. Volume 26 of Issue 19. 2006. PMID: 16980629
Zimmerman ES, Sherman MP, Blackett JL, Neidleman JA, Kreis C, Mundt P, Williams SA, Warmerdam M, Kahn J, Hecht FM, Grant RM, de Noronha CM, Weyrich AS, Greene WC, Planelles V. Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo. Volume 80 of Issue 21. Journal of virology 2006. PMID: 16956949
Soros VB, Greene WC. APOBEC3G and HIV-1: strike and counterstrike. Volume 8 of Issue 4. 2006. PMID: 16822376
Chiu YL, Greene WC. Multifaceted antiviral actions of APOBEC3 cytidine deaminases. Volume 27 of Issue 6. 2006. PMID: 16678488
Kreisberg JF, Yonemoto W, Greene WC. Endogenous factors enhance HIV infection of tissue naive CD4 T cells by stimulating high molecular mass APOBEC3G complex formation. Volume 203 of Issue 4. 2006. PMID: 16606671
Chandrasekar B, Mummidi S, Mahimainathan L, Patel DN, Bailey SR, Imam SZ, Greene WC, Valente AJ. Interleukin-18-induced human coronary artery smooth muscle cell migration is dependent on NF-kappaB- and AP-1-mediated matrix metalloproteinase-9 expression and is inhibited by atorvastatin. Volume 281 of Issue 22. The Journal of biological chemistry 2006. PMID: 16554298
Cavrois M, Neidleman J, Kreisberg JF, Fenard D, Callebaut C, Greene WC. Human immunodeficiency virus fusion to dendritic cells declines as cells mature. Volume 80 of Issue 4. Journal of virology 2006. PMID: 16439555
Chiu YL, Greene WC. APOBEC3 cytidine deaminases: distinct antiviral actions along the retroviral life cycle. Volume 281 of Issue 13. The Journal of biological chemistry 2005. PMID: 16407183
Williams SA, Chen LF, Kwon H, Ruiz-Jarabo CM, Verdin E, Greene WC. NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. Volume 25 of Issue 1. 2005. PMID: 16319923
Fenard D, Yonemoto W, de Noronha C, Cavrois M, Williams SA, Greene WC. Nef is physically recruited into the immunological synapse and potentiates T cell activation early after TCR engagement. Volume 175 of Issue 9. Journal of immunology (Baltimore, Md. : 1950) 2005. PMID: 16237100
Chen LF, Williams SA, Mu Y, Nakano H, Duerr JM, Buckbinder L, Greene WC. NF-kappaB RelA phosphorylation regulates RelA acetylation. Volume 25 of Issue 18. 2005. PMID: 16135789
Kwon H, Ogle L, Benitez B, Bohuslav J, Montano M, Felsher DW, Greene WC. Lethal cutaneous disease in transgenic mice conditionally expressing type I human T cell leukemia virus Tax. Volume 280 of Issue 42. The Journal of biological chemistry 2005. PMID: 16105841
Chen LF, Greene WC. Assessing acetylation of NF-kappaB. Volume 36 of Issue 4. 2005. PMID: 16111893
Williams SA, Greene WC. Host factors regulating post-integration latency of HIV. Volume 13 of Issue 4. Trends in microbiology 2005. PMID: 15817380
Stopak K, Greene WC. Protecting APOBEC3G: a potential new target for HIV drug discovery. Volume 6 of Issue 2. Current opinion in investigational drugs (London, England : 2000) 2005. PMID: 15751736
Keppler OT, Allespach I, Schüller L, Fenard D, Greene WC, Fackler OT. Rodent cells support key functions of the human immunodeficiency virus type 1 pathogenicity factor Nef. Volume 79 of Issue 3. Journal of virology 2005. PMID: 15650191
Yonezawa A, Cavrois M, Greene WC. Studies of ebola virus glycoprotein-mediated entry and fusion by using pseudotyped human immunodeficiency virus type 1 virions: involvement of cytoskeletal proteins and enhancement by tumor necrosis factor alpha. Volume 79 of Issue 2. Journal of virology 2005. PMID: 15613320
Cavrois M, Neidleman J, Yonemoto W, Fenard D, Greene WC. HIV-1 virion fusion assay: uncoating not required and no effect of Nef on fusion. Volume 328 of Issue 1. 2004. PMID: 15380356
Greene WC. The brightening future of HIV therapeutics. Volume 5 of Issue 9. 2004. PMID: 15334078
Greene WC. Redistricting the retroviral restriction factors. Volume 10 of Issue 8. Nature medicine 2004. PMID: 15286773
Williams SA, Chen LF, Kwon H, Fenard D, Bisgrove D, Verdin E, Greene WC. Prostratin antagonizes HIV latency by activating NF-kappaB. Volume 279 of Issue 40. The Journal of biological chemistry 2004. PMID: 15284245
Chen LF, Greene WC. Shaping the nuclear action of NF-kappaB. Volume 5 of Issue 5. 2004. PMID: 15122352
Bohuslav J, Chen LF, Kwon H, Mu Y, Greene WC. p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1. Volume 279 of Issue 25. The Journal of biological chemistry 2004. PMID: 15073170
O'Mahony AM, Montano M, Van Beneden K, Chen LF, Greene WC. Human T-cell lymphotropic virus type 1 tax induction of biologically Active NF-kappaB requires IkappaB kinase-1-mediated phosphorylation of RelA/p65. Volume 279 of Issue 18. The Journal of biological chemistry 2004. PMID: 14963024
Schaeffer E, Soros VB, Greene WC. Compensatory link between fusion and endocytosis of human immunodeficiency virus type 1 in human CD4 T lymphocytes. Volume 78 of Issue 3. Journal of virology 2004. PMID: 14722292
Cavrois M, Neidleman J, Bigos M, Greene WC. Fluorescence resonance energy transfer-based HIV-1 virion fusion assay. Volume 263. 2004. PMID: 14976375
Greene WC. How resting T cells deMURR HIV infection. Volume 5 of Issue 1. 2004. PMID: 14699403
Greene WC, Chen LF. Regulation of NF-kappaB action by reversible acetylation. Volume 259. 2004. PMID: 15171256
Stopak K, de Noronha C, Yonemoto W, Greene WC. HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability. Volume 12 of Issue 3. 2003. PMID: 14527406
Chen LF, Greene WC. Regulation of distinct biological activities of the NF-kappaB transcription factor complex by acetylation. Volume 81 of Issue 9. 2003. PMID: 12920522
Zander K, Sherman MP, Tessmer U, Bruns K, Wray V, Prechtel AT, Schubert E, Henklein P, Luban J, Neidleman J, Greene WC, Schubert U. Cyclophilin A interacts with HIV-1 Vpr and is required for its functional expression. Volume 278 of Issue 44. The Journal of biological chemistry 2003. PMID: 12881522
Sherman MP, de Noronha CM, Eckstein LA, Hataye J, Mundt P, Williams SA, Neidleman JA, Goldsmith MA, Greene WC. Nuclear export of Vpr is required for efficient replication of human immunodeficiency virus type 1 in tissue macrophages. Volume 77 of Issue 13. Journal of virology 2003. PMID: 12805458
Stoddart CA, Geleziunas R, Ferrell S, Linquist-Stepps V, Moreno ME, Bare C, Xu W, Yonemoto W, Bresnahan PA, McCune JM, Greene WC. Human immunodeficiency virus type 1 Nef-mediated downregulation of CD4 correlates with Nef enhancement of viral pathogenesis. Volume 77 of Issue 3. Journal of virology 2003. PMID: 12525647
Greene WC, Peterlin BM. Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy. Volume 8 of Issue 7. Nature medicine 2002. PMID: 12091904
Eckstein DA, Sherman MP, Penn ML, Chin PS, De Noronha CM, Greene WC, Goldsmith MA. HIV-1 Vpr enhances viral burden by facilitating infection of tissue macrophages but not nondividing CD4+ T cells. The Journal of experimental medicine 2001. PMID: 11714748
de Noronha CM, Sherman MP, Lin HW, Cavrois MV, Moir RD, Goldman RD, Greene WC. Dynamic disruptions in nuclear envelope architecture and integrity induced by HIV-1 Vpr. Science (New York, N.Y.) 2001. PMID: 11691994
. Duration of nuclear NF-kappaB action regulated by reversible acetylation. Volume 293 of Issue 5535. 2001. PMID: 11533489
Geleziunas R, Xu W, Takeda K, Ichijo H, Greene WC. HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell. Volume 410 of Issue 6830. 2001. PMID: 11298454
Schaeffer E, Geleziunas R, Greene WC. Human immunodeficiency virus type 1 Nef functions at the level of virus entry by enhancing cytoplasmic delivery of virions. Journal of virology 2001. PMID: 11222724
Sherman MP, de Noronha CM, Heusch MI, Greene S, Greene WC. Nucleocytoplasmic shuttling by human immunodeficiency virus type 1 Vpr. Journal of virology 2001. PMID: 11152524
Foehr ED, Bohuslav J, Chen LF, DeNoronha C, Geleziunas R, Lin X, O'Mahony A, Greene WC. The NF-kappa B-inducing kinase induces PC12 cell differentiation and prevents apoptosis. The Journal of biological chemistry 2000. PMID: 10980190
Foehr ED, Lin X, O'Mahony A, Geleziunas R, Bradshaw RA, Greene WC. NF-kappa B signaling promotes both cell survival and neurite process formation in nerve growth factor-stimulated PC12 cells. The Journal of neuroscience : the official journal of the Society for Neuroscience 2000. PMID: 11027214
Henklein P, Bruns K, Sherman MP, Tessmer U, Licha K, Kopp J, de Noronha CM, Greene WC, Wray V, Schubert U. Functional and structural characterization of synthetic HIV-1 Vpr that transduces cells, localizes to the nucleus, and induces G2 cell cycle arrest. Volume 275 of Issue 41. The Journal of biological chemistry 2000. PMID: 10903315
Lin L, DeMartino GN, Greene WC. Cotranslational dimerization of the Rel homology domain of NF-kappaB1 generates p50-p105 heterodimers and is required for effective p50 production. The EMBO journal 2000. PMID: 10970863
Sherman MP, de Noronha CM, Pearce D, Greene WC. Human immunodeficiency virus type 1 Vpr contains two leucine-rich helices that mediate glucocorticoid receptor coactivation independently of its effects on G(2) cell cycle arrest. Journal of virology 2000. PMID: 10933727
Lin X, O'Mahony A, Mu Y, Geleziunas R, Greene WC. Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta. Molecular and cellular biology 2000. PMID: 10733597
O'Mahony A, Lin X, Geleziunas R, Greene WC. Activation of the heterodimeric IkappaB kinase alpha (IKKalpha)-IKKbeta complex is directional: IKKalpha regulates IKKbeta under both basal and stimulated conditions. Molecular and cellular biology 2000. PMID: 10648602
Heusch M, Lin L, Geleziunas R, Greene WC. The generation of nfkb2 p52: mechanism and efficiency. Oncogene 1999. PMID: 10597218
Bresnahan PA, Yonemoto W, Greene WC. Cutting edge: SIV Nef protein utilizes both leucine- and tyrosine-based protein sorting pathways for down-regulation of CD4. Journal of immunology (Baltimore, Md. : 1950) 1999. PMID: 10477559
Lin X, Cunningham ET, Mu Y, Geleziunas R, Greene WC. The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-kappaB acting through the NF-kappaB-inducing kinase and IkappaB kinases. Immunity 1999. PMID: 10072079
Jenkins Y, McEntee M, Weis K, Greene WC. Characterization of HIV-1 vpr nuclear import: analysis of signals and pathways. The Journal of cell biology 1998. PMID: 9817747
Bresnahan PA, Yonemoto W, Ferrell S, Williams-Herman D, Geleziunas R, Greene WC. A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor. Current biology : CB 1998. PMID: 9811606
Lin X, Mu Y, Cunningham ET, Marcu KB, Geleziunas R, Greene WC. Molecular determinants of NF-kappaB-inducing kinase action. Molecular and cellular biology 1998. PMID: 9742107
Liegler TJ, Yonemoto W, Elbeik T, Vittinghoff E, Buchbinder SP, Greene WC. Diminished spontaneous apoptosis in lymphocytes from human immunodeficiency virus-infected long-term nonprogressors. The Journal of infectious diseases 1998. PMID: 9728534
Geleziunas R, Ferrell S, Lin X, Mu Y, Cunningham ET, Grant M, Connelly MA, Hambor JE, Marcu KB, Greene WC. Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases. Molecular and cellular biology 1998. PMID: 9710600
Lin L, DeMartino GN, Greene WC. Cotranslational biogenesis of NF-kappaB p50 by the 26S proteasome. Cell 1998. PMID: 9529257
Liu KD, Gaffen SL, Goldsmith MA, Greene WC. Janus kinases in interleukin-2-mediated signaling: JAK1 and JAK3 are differentially regulated by tyrosine phosphorylation. Volume 7 of Issue 11. Current biology : CB 1997. PMID: 9382798
Ghoda L, Lin X, Greene WC. The 90-kDa ribosomal S6 kinase (pp90rsk) phosphorylates the N-terminal regulatory domain of IkappaBalpha and stimulates its degradation in vitro. Volume 272 of Issue 34. The Journal of biological chemistry 1997. PMID: 9261139
Miller MD, Warmerdam MT, Ferrell SS, Benitez R, Greene WC. Intravirion generation of the C-terminal core domain of HIV-1 Nef by the HIV-1 protease is insufficient to enhance viral infectivity. Volume 234 of Issue 2. 1997. PMID: 9268152
Powell DM, Amaral MC, Wu JY, Maniatis T, Greene WC. HIV Rev-dependent binding of SF2/ASF to the Rev response element: possible role in Rev-mediated inhibition of HIV RNA splicing. Proceedings of the National Academy of Sciences of the United States of America 1997. PMID: 9023367
Tie F, Adya N, Greene WC, Giam CZ. Interaction of the human T-lymphotropic virus type 1 Tax dimer with CREB and the viral 21-base-pair repeat. Volume 70 of Issue 12. Journal of virology 1996. PMID: 8970957
Geleziunas R, Miller MD, Greene WC. Unraveling the function of HIV type 1 Nef. AIDS research and human retroviruses 1996. PMID: 8947291
Shapiro VS, Mollenauer MN, Greene WC, Weiss A. c-rel regulation of IL-2 gene expression may be mediated through activation of AP-1. The Journal of experimental medicine 1996. PMID: 8920856
Gaffen SL, Lai SY, Ha M, Liu X, Hennighausen L, Greene WC, Goldsmith MA. Distinct tyrosine residues within the interleukin-2 receptor beta chain drive signal transduction specificity, redundancy, and diversity. Volume 271 of Issue 35. The Journal of biological chemistry 1996. PMID: 8702919
Kim JH, McLinden RJ, Mosca JD, Vahey MT, Greene WC, Redfield RR. Inhibition of HIV replication by sense and antisense rev response elements in HIV-based retroviral vectors. Volume 12 of Issue 4. 1996. PMID: 8673542
Liu KD, Greene WC, Goldsmith MA. The alpha chain of the IL-2 receptor determines the species specificity of high-affinity IL-2 binding. Cytokine 1996. PMID: 8894436
Greene WC. Denying HIV safe haven. Volume 334 of Issue 19. The New England journal of medicine 1996. PMID: 8606724
Hsu DK, Hammes SR, Kuwabara I, Greene WC, Liu FT. Human T lymphotropic virus-I infection of human T lymphocytes induces expression of the beta-galactoside-binding lectin, galectin-3. Volume 148 of Issue 5. 1996. PMID: 8623933
Miller MD, Greene WC. Is the Nef protein of HIV-1 required for pathogenesis? Trends in microbiology 1996. PMID: 8727595
Sun S, Elwood J, Greene WC. Both amino- and carboxyl-terminal sequences within I kappa B alpha regulate its inducible degradation. Volume 16 of Issue 3. 1996. PMID: 8622650
Lai SY, Xu W, Gaffen SL, Liu KD, Longmore GD, Greene WC, Goldsmith MA. The molecular role of the common gamma c subunit in signal transduction reveals functional asymmetry within multimeric cytokine receptor complexes. Volume 93 of Issue 1. Proceedings of the National Academy of Sciences of the United States of America 1996. PMID: 8552611
Béraud C, Greene WC. Interaction of HTLV-I Tax with the human proteasome: implications for NF-kappa B induction. Volume 13 Suppl 1. 1996. PMID: 8797708
Evans GA, Goldsmith MA, Johnston JA, Xu W, Weiler SR, Erwin R, Howard OM, Abraham RT, O'Shea JJ, Greene WC. Analysis of interleukin-2-dependent signal transduction through the Shc/Grb2 adapter pathway. Interleukin-2-dependent mitogenesis does not require Shc phosphorylation or receptor association. Volume 270 of Issue 48. The Journal of biological chemistry 1995. PMID: 7499411
Greene WC. Predicting progression to AIDS. Volume 123 of Issue 9. Annals of internal medicine 1995. PMID: 7574230
Liu KD, Lai SY, Goldsmith MA, Greene WC. Identification of a variable region within the cytoplasmic tail of the IL-2 receptor beta chain that is required for growth signal transduction. The Journal of biological chemistry 1995. PMID: 7545674
Goldsmith MA, Lai SY, Xu W, Amaral MC, Kuczek ES, Parent LJ, Mills GB, Tarr KL, Longmore GD, Greene WC. Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the beta chain and non-tyrosine residues of the gamma c chain. The Journal of biological chemistry 1995. PMID: 7665592
Gaffen SL, Lai SY, Xu W, Gouilleux F, Groner B, Goldsmith MA, Greene WC. Signaling through the interleukin 2 receptor beta chain activates a STAT-5-like DNA-binding activity. Proceedings of the National Academy of Sciences of the United States of America 1995. PMID: 7543676
Goldsmith MA, Warmerdam MT, Atchison RE, Miller MD, Greene WC. Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef. Journal of virology 1995. PMID: 7769669
Goldsmith MA, Amaral MC, Greene WC. Ligand binding by the IL-2 receptor is modulated by intracellular determinants of the IL-2 receptor beta-chain. Journal of immunology (Baltimore, Md. : 1950) 1995. PMID: 7868880
Miller MD, Warmerdam MT, Page KA, Feinberg MB, Greene WC. Expression of the human immunodeficiency virus type 1 (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp160 or viral entry. Volume 69 of Issue 1. Journal of virology 1995. PMID: 7983759
Sun SC, Elwood J, Béraud C, Greene WC. Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel gene. Molecular and cellular biology 1994. PMID: 7935451
Miller MD, Feinberg MB, Greene WC. The HIV-1 nef gene acts as a positive viral infectivity factor. Volume 2 of Issue 8. Trends in microbiology 1994. PMID: 7981973
Goldsmith MA, Xu W, Amaral MC, Kuczek ES, Greene WC. The cytoplasmic domain of the interleukin-2 receptor beta chain contains both unique and functionally redundant signal transduction elements. The Journal of biological chemistry 1994. PMID: 8182077
Williamson P, Merida I, Greene WC, Gaulton G. The membrane proximal segment of the IL-2 receptor beta-chain acidic region is essential for IL2-dependent protein tyrosine kinase activation. Volume 8 Suppl 1. Leukemia 1994. PMID: 8152289
Sun SC, Ganchi PA, Béraud C, Ballard DW, Greene WC. Autoregulation of the NF-kappa B transactivator RelA (p65) by multiple cytoplasmic inhibitors containing ankyrin motifs. Proceedings of the National Academy of Sciences of the United States of America 1994. PMID: 8108414
Béraud C, Sun SC, Ganchi P, Ballard DW, Greene WC. Human T-cell leukemia virus type I Tax associates with and is negatively regulated by the NF-kappa B2 p100 gene product: implications for viral latency. Molecular and cellular biology 1994. PMID: 8289813
Miller MD, Warmerdam MT, Gaston I, Greene WC, Feinberg MB. The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages. Volume 179 of Issue 1. 1994. PMID: 8270859
Ganchi PA, Sun SC, Greene WC, Ballard DW. A novel NF-kappa B complex containing p65 homodimers: implications for transcriptional control at the level of subunit dimerization. Molecular and cellular biology 1993. PMID: 8246997
Stein B, Baldwin AS, Ballard DW, Greene WC, Angel P, Herrlich P. Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function. Volume 12 of Issue 10. 1993. PMID: 8404856
Greene WC. AIDS and the immune system. Volume 269 of Issue 3. 1993. PMID: 8211096
Bogerd H, Greene WC. Dominant negative mutants of human T-cell leukemia virus type I Rex and human immunodeficiency virus type 1 Rev fail to multimerize in vivo. Volume 67 of Issue 5. Journal of virology 1993. PMID: 8474155
Kuziel WA, Ju G, Grdina TA, Greene WC. Unexpected effects of the IL-2 receptor alpha subunit on high affinity IL-2 receptor assembly and function detected with a mutant IL-2 analog. Volume 150 of Issue 8 Pt 1. Journal of immunology (Baltimore, Md. : 1950) 1993. PMID: 8468475
Sun SC, Ganchi PA, Ballard DW, Greene WC. NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway. Science (New York, N.Y.) 1993. PMID: 8096091
Merida I, Williamson P, Kuziel WA, Greene WC, Gaulton GN. The serine-rich cytoplasmic domain of the interleukin-2 receptor beta chain is essential for interleukin-2-dependent tyrosine protein kinase and phosphatidylinositol-3-kinase activation. Volume 268 of Issue 9. The Journal of biological chemistry 1993. PMID: 8384218
Hammes SR, Greene WC. Multiple arginine residues within the basic domain of HTLV-I Rex are required for specific RNA binding and function. Volume 193 of Issue 1. 1993. PMID: 8438577
Doerre S, Sista P, Sun SC, Ballard DW, Greene WC. The c-rel protooncogene product represses NF-kappa B p65-mediated transcriptional activation of the long terminal repeat of type 1 human immunodeficiency virus. Volume 90 of Issue 3. Proceedings of the National Academy of Sciences of the United States of America 1993. PMID: 8430069
Ganchi PA, Sun SC, Greene WC, Ballard DW. I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding. Molecular biology of the cell 1992. PMID: 1493333
Mills GB, Arima N, May C, Hill M, Schmandt R, Li J, Miyamoto NG, Greene WC. Neither the LCK nor the FYN kinases are obligatory for IL-2-mediated signal transduction in HTLV-I-infected human T cells. Volume 4 of Issue 11. 1992. PMID: 1472476
Feinberg MB, Greene WC. Molecular insights into human immunodeficiency virus type 1 pathogenesis. Current opinion in immunology 1992. PMID: 1356348
Walker WH, Stein B, Ganchi PA, Hoffman JA, Kaufman PA, Ballard DW, Hannink M, Greene WC. The v-rel oncogene: insights into the mechanism of transcriptional activation, repression, and transformation. Volume 66 of Issue 8. Journal of virology 1992. PMID: 1321284
Weichselbraun I, Berger J, Dobrovnik M, Bogerd H, Grassmann R, Greene WC, Hauber J, Böhnlein E. Dominant-negative mutants are clustered in a domain of the human T-cell leukemia virus type I Rex protein: implications for trans dominance. Volume 66 of Issue 7. Journal of virology 1992. PMID: 1602559
Arima N, Kuziel WA, Grdina TA, Greene WC. IL-2-induced signal transduction involves the activation of nuclear NF-kappa B expression. Volume 149 of Issue 1. Journal of immunology (Baltimore, Md. : 1950) 1992. PMID: 1607664
Kaufman PA, Weinberg JB, Greene WC. Nuclear expression of the 50- and 65-kD Rel-related subunits of nuclear factor-kappa B is differentially regulated in human monocytic cells. Volume 90 of Issue 1. The Journal of clinical investigation 1992. PMID: 1634604
Smith MR, Greene WC. Characterization of a novel nuclear localization signal in the HTLV-I tax transactivator protein. Volume 187 of Issue 1. 1992. PMID: 1736534
Ballard DW, Dixon EP, Peffer NJ, Bogerd H, Doerre S, Stein B, Greene WC. The 65-kDa subunit of human NF-kappa B functions as a potent transcriptional activator and a target for v-Rel-mediated repression. Volume 89 of Issue 5. Proceedings of the National Academy of Sciences of the United States of America 1992. PMID: 1542686
Arima N, Molitor JA, Smith MR, Kim JH, Daitoku Y, Greene WC. Human T-cell leukemia virus type I Tax induces expression of the Rel-related family of kappa B enhancer-binding proteins: evidence for a pretranslational component of regulation. Volume 65 of Issue 12. Journal of virology 1991. PMID: 1719236
Molitor JA, Ballard DW, Greene WC. Kappa B-specific DNA binding proteins are differentially inhibited by enhancer mutations and biological oxidation. Volume 3 of Issue 10. 1991. PMID: 1768652
Smith MR, Greene WC. Type I human T cell leukemia virus tax protein transforms rat fibroblasts through the cyclic adenosine monophosphate response element binding protein/activating transcription factor pathway. Volume 88 of Issue 3. The Journal of clinical investigation 1991. PMID: 1832173
Bogerd HP, Huckaby GL, Ahmed YF, Hanly SM, Greene WC. The type I human T-cell leukemia virus (HTLV-I) Rex trans-activator binds directly to the HTLV-I Rex and the type 1 human immunodeficiency virus Rev RNA response elements. Volume 88 of Issue 13. Proceedings of the National Academy of Sciences of the United States of America 1991. PMID: 1905815
Lee JH, Li YC, Doerre S, Sista P, Ballard DW, Greene WC, Franza BR. A member of the set of kappa B binding proteins, HIVEN86A, is a product of the human c-rel proto-oncogene. Volume 6 of Issue 4. 1991. PMID: 2030915
Hémar A, Cereghini S, Cornet V, Blank V, Israël A, Greene WC, Dautry-Varsat A. Kappa B binding proteins are constitutively expressed in an IL-2 autocrine human T cell line. Volume 146 of Issue 7. Journal of immunology (Baltimore, Md. : 1950) 1991. PMID: 2005404
Smith MR, Greene WC. Molecular biology of the type I human T-cell leukemia virus (HTLV-I) and adult T-cell leukemia. Volume 87 of Issue 3. The Journal of clinical investigation 1991. PMID: 1999493
Ahmed YF, Gilmartin GM, Hanly SM, Nevins JR, Greene WC. The HTLV-I Rex response element mediates a novel form of mRNA polyadenylation. Volume 64 of Issue 4. 1991. PMID: 1671761
Greene WC. The molecular biology of human immunodeficiency virus type 1 infection. Volume 324 of Issue 5. The New England journal of medicine 1991. PMID: 1986289
Smith MR, Greene WC. Functional analyses of the type I human T-cell leukemia virus tax gene product. Volume 104. 1991. PMID: 1845158
Kim JH, Kaufman PA, Hanly SM, Rimsky LT, Greene WC. Rex transregulation of human T-cell leukemia virus type II gene expression. Volume 65 of Issue 1. Journal of virology 1991. PMID: 1985205
Molitor JA, Walker WH, Doerre S, Ballard DW, Greene WC. NF-kappa B: a family of inducible and differentially expressed enhancer-binding proteins in human T cells. Volume 87 of Issue 24. Proceedings of the National Academy of Sciences of the United States of America 1990. PMID: 2263603
Ballard DW, Walker WH, Doerre S, Sista P, Molitor JA, Dixon EP, Peffer NJ, Hannink M, Greene WC. The v-rel oncogene encodes a kappa B enhancer binding protein that inhibits NF-kappa B function. Volume 63 of Issue 4. 1990. PMID: 2225078
Smith MR, Greene WC. Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes. Volume 4 of Issue 11. 1990. PMID: 2276622
Cullen BR, Greene WC. Functions of the auxiliary gene products of the human immunodeficiency virus type 1. Volume 178 of Issue 1. 1990. PMID: 2202146
Rubin LA, Galli F, Greene WC, Nelson DL, Jay G. The molecular basis for the generation of the human soluble interleukin 2 receptor. Volume 2 of Issue 5. Cytokine 1990. PMID: 2103332
Kuziel WA, Greene WC. Interleukin-2 and the IL-2 receptor: new insights into structure and function. Volume 94 of Issue 6 Suppl. 1990. PMID: 1693645
Ahmed YF, Hanly SM, Malim MH, Cullen BR, Greene WC. Structure-function analyses of the HTLV-I Rex and HIV-1 Rev RNA response elements: insights into the mechanism of Rex and Rev action. Volume 4 of Issue 6. 1990. PMID: 2116986
Fung MR, Greene WC. The human interleukin-2 receptor: insights into subunit structure and growth signal transduction. Volume 2 of Issue 2. 1990. PMID: 2129904
Mills GB, May C, McGill M, Fung M, Baker M, Sutherland R, Greene WC. Interleukin 2-induced tyrosine phosphorylation. Interleukin 2 receptor beta is tyrosine phosphorylated. Volume 265 of Issue 6. The Journal of biological chemistry 1990. PMID: 2303462
Greene WC. Regulation of HIV-1 gene expression. Volume 8. 1990. PMID: 2188670
Pomerantz JL, Mauxion F, Yoshida M, Greene WC, Sen R. A second sequence element located 3' to the NF-kappa B-binding site regulates IL-2 receptor-alpha gene induction. Volume 143 of Issue 12. Journal of immunology (Baltimore, Md. : 1950) 1989. PMID: 2687377
Hammes SR, Dixon EP, Malim MH, Cullen BR, Greene WC. Nef protein of human immunodeficiency virus type 1: evidence against its role as a transcriptional inhibitor. Volume 86 of Issue 23. Proceedings of the National Academy of Sciences of the United States of America 1989. PMID: 2687884
Smith MR, Greene WC. The same 50-kDa cellular protein binds to the negative regulatory elements of the interleukin 2 receptor alpha-chain gene and the human immunodeficiency virus type 1 long terminal repeat. Volume 86 of Issue 21. Proceedings of the National Academy of Sciences of the United States of America 1989. PMID: 2813410
Rimsky L, Dodon MD, Dixon EP, Greene WC. Trans-dominant inactivation of HTLV-I and HIV-1 gene expression by mutation of the HTLV-I Rex transactivator. Volume 341 of Issue 6241. 1989. PMID: 2677743
Ballard DW, Böhnlein E, Hoffman JA, Bogerd HP, Dixon EP, Franza BR, Greene WC. Activation of the interleukin-2 receptor alpha gene: regulatory role for DNA-protein interactions flanking the kappa B enhancer. Volume 1 of Issue 1. 1989. PMID: 2518691
Hanly SM, Rimsky LT, Malim MH, Kim JH, Hauber J, Duc Dodon M, Le SY, Maizel JV, Cullen BR, Greene WC. Comparative analysis of the HTLV-I Rex and HIV-1 Rev trans-regulatory proteins and their RNA response elements. Volume 3 of Issue 10. 1989. PMID: 2482226
Cullen BR, Greene WC. Regulatory pathways governing HIV-1 replication. Volume 58 of Issue 3. 1989. PMID: 2569361
Greene WC, Böhnlein E, Ballard DW. HIV-1, HTLV-1 and normal T-cell growth: transcriptional strategies and surprises. Volume 10 of Issue 8. 1989. PMID: 2679647
Böhnlein E, Ballard DW, Bogerd H, Peffer NJ, Lowenthal JW, Greene WC. Induction of interleukin-2 receptor-alpha gene expression is regulated by post-translational activation of kappa B specific DNA binding proteins. Volume 264 of Issue 15. The Journal of biological chemistry 1989. PMID: 2785992
Lowenthal JW, Ballard DW, Bogerd H, Böhnlein E, Greene WC. Tumor necrosis factor-alpha activation of the IL-2 receptor-alpha gene involves the induction of kappa B-specific DNA binding proteins. Volume 142 of Issue 9. Journal of immunology (Baltimore, Md. : 1950) 1989. PMID: 2785134
Hoyos B, Ballard DW, Böhnlein E, Siekevitz M, Greene WC. Kappa B-specific DNA binding proteins: role in the regulation of human interleukin-2 gene expression. Volume 244 of Issue 4903. 1989. PMID: 2497518
Böhnlein E, Siekevitz M, Ballard DW, Lowenthal JW, Rimsky L, Bogérd H, Hoffman J, Wano Y, Franza BR, Greene WC. Stimulation of the human immunodeficiency virus type 1 enhancer by the human T-cell leukemia virus type I tax gene product involves the action of inducible cellular proteins. Volume 63 of Issue 4. Journal of virology 1989. PMID: 2784507
Lowenthal JW, Ballard DW, Böhnlein E, Greene WC. Tumor necrosis factor alpha induces proteins that bind specifically to kappa B-like enhancer elements and regulate interleukin 2 receptor alpha-chain gene expression in primary human T lymphocytes. Volume 86 of Issue 7. Proceedings of the National Academy of Sciences of the United States of America 1989. PMID: 2494663
Böhnlein E, Lowenthal JW, Wano Y, Franza BR, Ballard DW, Greene WC. HIV-1, HTLV-I and the interleukin-2 receptor: insights into transcriptional control. Volume 32. 1989. PMID: 2625257
Wano Y, Feinberg M, Hosking JB, Bogerd H, Greene WC. Stable expression of the tax gene of type I human T-cell leukemia virus in human T cells activates specific cellular genes involved in growth. Volume 85 of Issue 24. Proceedings of the National Academy of Sciences of the United States of America 1988. PMID: 3059351
Fung MR, Ju G, Greene WC. Co-internalization of the p55 and p70 subunits of the high-affinity human interleukin 2 receptor. Evidence for a stable ternary receptor complex. Volume 168 of Issue 5. 1988. PMID: 3263468
Rimsky L, Hauber J, Dukovich M, Malim MH, Langlois A, Cullen BR, Greene WC. Functional replacement of the HIV-1 rev protein by the HTLV-1 rex protein. Volume 335 of Issue 6192. 1988. PMID: 3262832
Collins L, Tsien WH, Seals C, Hakimi J, Weber D, Bailon P, Hoskings J, Greene WC, Toome V, Ju G. Identification of specific residues of human interleukin 2 that affect binding to the 70-kDa subunit (p70) of the interleukin 2 receptor. Volume 85 of Issue 20. Proceedings of the National Academy of Sciences of the United States of America 1988. PMID: 3051003
Ballard DW, Böhnlein E, Lowenthal JW, Wano Y, Franza BR, Greene WC. HTLV-I tax induces cellular proteins that activate the kappa B element in the IL-2 receptor alpha gene. Volume 241 of Issue 4873. 1988. PMID: 2843985
Froussard P, Chastagner P, Sommé G, Abadie A, Greene W, Thèze J, Longacre S. p55 IL-2 receptor mRNA precursors in murine T lymphocyte nuclei. Volume 141 of Issue 4. Journal of immunology (Baltimore, Md. : 1950) 1988. PMID: 3135330
Böhnlein E, Lowenthal JW, Siekevitz M, Ballard DW, Franza BR, Greene WC. The same inducible nuclear proteins regulates mitogen activation of both the interleukin-2 receptor-alpha gene and type 1 HIV. Volume 53 of Issue 5. 1988. PMID: 2836068
Lowenthal JW, Böhnlein E, Ballard DW, Greene WC. Regulation of interleukin 2 receptor alpha subunit (Tac or CD25 antigen) gene expression: binding of inducible nuclear proteins to discrete promoter sequences correlates with transcriptional activation. Volume 85 of Issue 12. Proceedings of the National Academy of Sciences of the United States of America 1988. PMID: 3132714
Cullen BR, Podlaski FJ, Peffer NJ, Hosking JB, Greene WC. Sequence requirements for ligand binding and cell surface expression of the Tac antigen, a human interleukin-2 receptor. Volume 263 of Issue 10. The Journal of biological chemistry 1988. PMID: 2832410
Greene WC. Sarcoidosis and interleukin-2 receptors. Volume 137 of Issue 4. The American review of respiratory disease 1988. PMID: 2833139
Zeitz M, Greene WC, Peffer NJ, James SP. Lymphocytes isolated from the intestinal lamina propria of normal nonhuman primates have increased expression of genes associated with T-cell activation. Volume 94 of Issue 3. Gastroenterology 1988. PMID: 3123303
Greene WC. In: Gallin J, Goldstein I, Snyderman R (Eds.), Inflammation: Basic principles and clinical correlations 1988. PMID:
Wano Y, Dukovich M, Kehrl JH, Greene WC. In: Smith KA (Ed.), Interleukin 2 1988. PMID:
Greene WC, Wano YJ, Dukovich M. New insights into the structure of high-affinity interleukin-2 receptors. Volume 44. 1988. PMID: 3064206
Kehrl JH, Dukovich M, Whalen G, Katz P, Fauci AS, Greene WC. Novel interleukin 2 (IL-2) receptor appears to mediate IL-2-induced activation of natural killer cells. Volume 81 of Issue 1. The Journal of clinical investigation 1988. PMID: 2826541
Greene WC, Böhnlein E, Siekevitz M, Franza BR, Lowenthal J. The human interleukin-2 receptor. Recent studies of structure and regulation. Volume 546. 1988. PMID: 3073691
Siekevitz M, Josephs SF, Dukovich M, Peffer N, Wong-Staal F, Greene WC. Activation of the HIV-1 LTR by T cell mitogens and the trans-activator protein of HTLV-I. Volume 238 of Issue 4833. 1987. PMID: 2825351
Lowenthal JW, Greene WC. Contrasting interleukin 2 binding properties of the alpha (p55) and beta (p70) protein subunits of the human high-affinity interleukin 2 receptor. Volume 166 of Issue 4. 1987. PMID: 3116145
Rubin LA, Hoekzema GS, Nelson DL, Greene WC, Jay G. Reconstitution of a functional interleukin 2 receptor in a nonlymphoid cell. Volume 139 of Issue 7. Journal of immunology (Baltimore, Md. : 1950) 1987. PMID: 2821112
Bich-Thuy LT, Dukovich M, Peffer NJ, Fauci AS, Kehrl JH, Greene WC. Direct activation of human resting T cells by IL 2: the role of an IL 2 receptor distinct from the Tac protein. Volume 139 of Issue 5. Journal of immunology (Baltimore, Md. : 1950) 1987. PMID: 3040856
Wano Y, Hattori T, Matsuoka M, Takatsuki K, Chua AO, Gubler U, Greene WC. Interleukin 1 gene expression in adult T cell leukemia. Volume 80 of Issue 3. The Journal of clinical investigation 1987. PMID: 2887587
Greene WC. The human interleukin-2 receptor: a molecular and biochemical analysis of structure and function. Volume 35 of Issue 5. 1987. PMID: 2889557
Siekevitz M, Feinberg MB, Holbrook N, Wong-Staal F, Greene WC. Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I. Volume 84 of Issue 15. Proceedings of the National Academy of Sciences of the United States of America 1987. PMID: 3037548
Dukovich M, Wano Y. A second human interleukin-2 binding protein that may be a component of high-affinity interleukin-2 receptors. Volume 327 of Issue 6122. 1987. PMID: 3108674
Holter W, Goldman CK, Casabo L, Nelson DL, Greene WC, Waldmann TA. Expression of functional IL 2 receptors by lipopolysaccharide and interferon-gamma stimulated human monocytes. Volume 138 of Issue 9. Journal of immunology (Baltimore, Md. : 1950) 1987. PMID: 3106493
Bernard O, Fazekas de St Groth B, Ullrich A, Green W, Schlessinger J. High-affinity interleukin 2 binding by an oncogenic hybrid interleukin 2-epidermal growth factor receptor molecule. Volume 84 of Issue 8. Proceedings of the National Academy of Sciences of the United States of America 1987. PMID: 3104909
Robb RJ, Rusk CM, Yodoi J, Greene WC. Interleukin 2 binding molecule distinct from the Tac protein: analysis of its role in formation of high-affinity receptors. Volume 84 of Issue 7. Proceedings of the National Academy of Sciences of the United States of America 1987. PMID: 3031660
Robb RJ, Greene WC. Internalization of interleukin 2 is mediated by the beta chain of the high-affinity interleukin 2 receptor. Volume 165 of Issue 4. 1987. PMID: 3031195
Wano Y, Cullen BR, Svetlik PA, Peffer NJ, Greene WC. Reconstitution of high affinity IL-2 receptor expression in a human T-cell line using a retroviral cDNA expression vector. Volume 4 of Issue 2. 1987. PMID: 3114593
Greene WC, Leonard WJ, Wano Y, Svetlik PB, Peffer NJ, Sodroski JG, Rosen CA, Goh WC, Haseltine WA. Trans-activator gene of HTLV-II: interpretation. Volume 235 of Issue 4792. 1987. PMID: 3029865
Greene WC. An overview of the human interleukin-2 receptor: molecular, biochemical, and functional properties. Volume 5 of Issue 4. Cancer investigation 1987. PMID: 2889515
Greene WC, Leonard WJ. Human interleukin 2 receptor (Tac antigen). Volume 150. 1987. PMID: 3123879
Greene WC, Leonard WJ, Wano Y, Sodroski JG, Rosen CA, Haseltine WA. In: Pruzanki W, Seligmann M (Eds.), Clinical Immunology 1987. PMID:
Greene WC, Dukovich M, Wano Y, Kehrl JH, Robb RJ. In: Webb DR, Pierce CW, Cohen S (Eds.), Proceedings of the Fifth International Lymphokine Workshop 1987. PMID:
Greene WC. Int. J. Immunother. III 1987. PMID:
Greene WC. Proceedings of the AACR 1987 1987. PMID:
Chanda PK, Chen GF, Baine Y, Leonard WJ, Greene WC, Chang TW, Chang NT. Expression of human interleukin-2 receptor cDNA in E. coli. Volume 141 of Issue 2. Biochemical and biophysical research communications 1986. PMID: 3026392
Neckers LM, Bauer S, McGlennen RC, Trepel JB, Rao K, Greene WC. Diltiazem inhibits transferrin receptor expression and causes G1 arrest in normal and neoplastic T cells. Volume 6 of Issue 12. 1986. PMID: 2432398
Greene WC. Characterization of the human interleukin 2 receptor at the DNA, RNA, and protein level. Volume 172 of Issue 3-5. 1986. PMID: 3100432
Greene WC, Depper JM, Krönke M, Leonard WJ. The human interleukin-2 receptor: analysis of structure and function. Volume 92. 1986. PMID: 3091481
Krönke M, Schlick E, Waldmann TA, Vitetta ES, Greene WC. Selective killing of human T-lymphotropic virus-I infected leukemic T-cells by monoclonal anti-interleukin 2 receptor antibody-ricin A chain conjugates: potentiation by ammonium chloride and monensin. Volume 46 of Issue 7. Cancer research 1986. PMID: 3011246
Treiger BF, Leonard WJ, Svetlik P, Rubin LA, Nelson DL, Greene WC. A secreted form of the human interleukin 2 receptor encoded by an "anchor minus" cDNA. Volume 136 of Issue 11. Journal of immunology (Baltimore, Md. : 1950) 1986. PMID: 3084654
Greene WC, Leonard WJ, Wano Y, Svetlik PB, Peffer NJ, Sodroski JG, Rosen CA, Goh WC, Haseltine WA. Trans-activator gene of HTLV-II induces IL-2 receptor and IL-2 cellular gene expression. Volume 232 of Issue 4752. 1986. PMID: 3010456
Weissman AM, Harford JB, Svetlik PB, Leonard WL, Depper JM, Waldmann TA, Greene WC, Klausner RD. Only high-affinity receptors for interleukin 2 mediate internalization of ligand. Volume 83 of Issue 5. Proceedings of the National Academy of Sciences of the United States of America 1986. PMID: 3081898
Greene WC, Leonard WJ, Depper JM. Growth of human T lymphocytes: an analysis of interleukin 2 and its cellular receptor. Volume 14. 1986. PMID: 2418464
Greene WC. In: Greene WC, moderator. The human interleukin-2 receptor: normal and abnormal expression in T cells and in leukemias induced by the human T lymphotropic retroviruses. Ann. Int. Med 1986. PMID:
Greene WC, Leonard WJ, Wano Y, Sodroski JG, Rosen CA, Haseltine WA. In: Marget M, Lang W, Gabler-Sandberger E (Eds.), Proceedings of the IXth International Congress of Infectious and Parasitic Diseases 1986. PMID:
Depper JM, Leonard WJ, Greene WC. In: Pincus S, Pisetsky D, Rosenwasser L (Eds.), Biologically based immunomodulators in the therapy of rheumatic diseases 1986. PMID:
Waldmann TA, Korsmeyer SJ, Greene WC. The arrangement of immunoglobulin, T cell antigen receptor, and interleukin 2 receptor genes in human lymphoid neoplasms. Volume 38. 1986. PMID: 3489263
Greene WC, Leonard WJ. The human interleukin-2 receptor. Volume 4. 1986. PMID: 3011033
Greene WC, Depper JM, Krönke M, Leonard WJ. The human interleukin-2 receptor: role in normal T-cell growth and association with HTLV-I-induced T-cell leukemia. Volume 51 Pt 2. 1986. PMID: 2884072
Leonard WJ, Depper JM, Kanehisa M, Krönke M, Peffer NJ, Svetlik PB, Sullivan M, Greene WC. Structure of the human interleukin-2 receptor gene. Volume 230 of Issue 4726. 1985. PMID: 2996141
Reed JC, Greene WC, Hoover RG, Nowell PC. Monoclonal antibody OKT11A inhibits and recombinant interleukin 2 (IL 2) augments expression of IL 2 receptors at a pretranslational level. Volume 135 of Issue 4. Journal of immunology (Baltimore, Md. : 1950) 1985. PMID: 3928749
Waldmann TA, Longo DL, Leonard WJ, Depper JM, Thompson CB, Krönke M, Goldman CK, Sharrow S, Bongiovanni K, Greene WC. Interleukin 2 receptor (Tac antigen) expression in HTLV-I-associated adult T-cell leukemia. Volume 45 of Issue 9 Suppl. Cancer research 1985. PMID: 2990687
Leonard WJ, Krönke M, Peffer NJ, Depper JM, Greene WC. Interleukin 2 receptor gene expression in normal human T lymphocytes. Volume 82 of Issue 18. Proceedings of the National Academy of Sciences of the United States of America 1985. PMID: 3929255
Greene WC, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Krönke M, Svetlik P, Peffer NJ, Waldmann TA. Isolation and expression of complementary DNAs encoding the human interleukin 2 receptor. Volume 45 of Issue 9 Suppl. Cancer research 1985. PMID: 2990688
Lane HC, Depper JM, Greene WC, Whalen G, Waldmann TA, Fauci AS. Qualitative analysis of immune function in patients with the acquired immunodeficiency syndrome. Evidence for a selective defect in soluble antigen recognition. Volume 313 of Issue 2. The New England journal of medicine 1985. PMID: 2582258
Greene WC, Robb RJ, Svetlik PB, Rusk CM, Depper JM, Leonard WJ. Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells. Volume 162 of Issue 1. 1985. PMID: 2989411
Leonard WJ, Donlon TA, Lebo RV, Greene WC. Localization of the gene encoding the human interleukin-2 receptor on chromosome 10. Volume 228 of Issue 4707. 1985. PMID: 3925551
Krönke M, Leonard WJ, Depper JM, Greene WC. Deregulation of interleukin-2 receptor gene expression in HTLV-I-induced adult T-cell leukemia. Volume 228 of Issue 4704. 1985. PMID: 2988127
Krönke M, Depper JM, Leonard WJ, Vitetta ES, Waldmann TA, Greene WC. Adult T cell leukemia: a potential target for ricin A chain immunotoxins. Volume 65 of Issue 6. Blood 1985. PMID: 2986744
Depper JM, Leonard WJ, Drogula C, Krönke M, Waldmann TA, Greene WC. Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene. Volume 82 of Issue 12. Proceedings of the National Academy of Sciences of the United States of America 1985. PMID: 2987968
Miller J, Malek TR, Leonard WJ, Greene WC, Shevach EM, Germain RN. Nucleotide sequence and expression of a mouse interleukin 2 receptor cDNA. Volume 134 of Issue 6. Journal of immunology (Baltimore, Md. : 1950) 1985. PMID: 3921620
Krönke M, Leonard WJ, Depper JM, Greene WC. Sequential expression of genes involved in human T lymphocyte growth and differentiation. Volume 161 of Issue 6. 1985. PMID: 2989408
Leonard WJ, Depper JM, Krönke M, Robb RJ, Waldmann TA, Greene WC. The human receptor for T-cell growth factor. Evidence for variable post-translational processing, phosphorylation, sulfation, and the ability of precursor forms of the receptor to bind T-cell growth factor. Volume 260 of Issue 3. The Journal of biological chemistry 1985. PMID: 2981876
Depper JM, Leonard WJ, Drogula CL, Krönke M, Waldmann TA, Greene WC. Activators of protein kinase C and 5-azacytidine induce IL-2 receptor expression on human T lymphocytes. Volume 27 of Issue 3. 1985. PMID: 2580852
Reed JC, Robb RJ, Greene WC, Nowell PC. Effect of wheat germ agglutinin on the interleukin pathway of human T lymphocyte activation. Volume 134 of Issue 1. Journal of immunology (Baltimore, Md. : 1950) 1985. PMID: 3917278
Waldmann TA, Leonard WJ, Depper JM, Kronke M, Kozak R, Greene WC. In: Cancer Cells 3: Growth factors and transformation 1985. PMID:
Waldmann TA, Leonard WJ, Depper JM, Kronke M, Goldman CK, Bongiovani KF, Greene WC.. In: Feldman M (Ed.), Human T cell clones: An approach to immune regulation 1985. PMID:
Leonard WJ, Depper JM, Crabtee GM, Rudikoff S, Pumphrey J, Robb RJ, Kronke M, Svetlik P, Peffer NJ, Waldmann TA, Greene WC. In: Feldmann M, Mitchison NA (Eds.), Immune Regulation 1985. PMID:
Greene WC, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Kronke M, Svetlik P, Peffer NJ, Waldmann TA, Leonard WJ. In: Pattengale PK, Lukes RJ, Taylor CR (Eds.), Lymphoproliferative Diseases: Pathogenesis, Diagnosis, and Therapy 1985. PMID:
Waldmann TA, Leonard WJ, Depper JM, Kronke M, Goldman CK, Sharrow S, Greene WC. In: Pinchera A, Doria G, Dammacco F, Bargellesi A (Eds.), Monoclonal Antibodies 1984: Biological and Clinical Applications 1985. PMID:
Kronke M, Depper JM, Leonard WJ, Wong-Staal F, Gallo RC, Waldmann TA, Greene WC. In: Sorg C, Schimple A (Eds.), Cellular and molecular biology of lymphokines 1985. PMID:
Leonard WJ, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Kronke M, Svetlik P, Peffer NJ, Waldmann TA, Greene WC. In: Sorg C, Schimple A (Eds.), Cellular and molecular biology of lymphokines 1985. PMID:
Depper JM, Leonard WJ, Kronke M, Waldmann TA, Greene WC. In: Sorg P, Schimple A (Eds.), Cellular and molecular biology of lymphokines 1985. PMID:
Greene WC, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Krönke M, Svetlik P, Peffer NJ, Waldmann TA. Molecular cloning of cDNA for the human interleukin-2 receptor. Volume 29. 1985. PMID: 2993133
Greene WC, Robb RJ. Receptors for T-cell growth factor: structure, function and expression on normal and neoplastic cells. Volume 10. 1985. PMID: 2983931
Greene WC, Depper JM, Krönke M, Leonard WJ. The human interleukin-2 receptor. Volume 3. 1985. PMID: 3938983
Korsmeyer SJ, Greene WC, Waldmann TA. Cellular origin of hairy cell leukemia: malignant B cells that express receptors for T cell growth factor. Volume 11 of Issue 4. 1984. PMID: 6438801
Depper JM, Leonard WJ, Krönke M, Noguchi PD, Cunningham RE, Waldmann TA, Greene WC. Regulation of interleukin 2 receptor expression: effects of phorbol diester, phospholipase C, and reexposure to lectin or antigen. Volume 133 of Issue 6. Journal of immunology (Baltimore, Md. : 1950) 1984. PMID: 6092466
Waldmann TA, Goldman CK, Robb RJ, Depper JM, Leonard WJ, Sharrow SO, Bongiovanni KF, Korsmeyer SJ, Greene WC. Expression of interleukin 2 receptors on activated human B cells. Volume 160 of Issue 5. 1984. PMID: 6092511
Depper JM, Leonard WJ, Krönke M, Waldmann TA, Greene WC. Augmented T cell growth factor receptor expression in HTLV-1-infected human leukemic T cells. Volume 133 of Issue 4. Journal of immunology (Baltimore, Md. : 1950) 1984. PMID: 6088625
Robb RJ, Greene WC, Rusk CM. Low and high affinity cellular receptors for interleukin 2. Implications for the level of Tac antigen. Volume 160 of Issue 4. 1984. PMID: 6090574
Leonard WJ, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Krönke M, Svetlik PB, Peffer NJ, Waldmann TA. Molecular cloning and expression of cDNAs for the human interleukin-2 receptor. Volume 311 of Issue 5987. 1984. PMID: 6090948
Krönke M, Leonard WJ, Depper JM, Arya SK, Wong-Staal F, Gallo RC, Waldmann TA, Greene WC. Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription. Volume 81 of Issue 16. Proceedings of the National Academy of Sciences of the United States of America 1984. PMID: 6332315
Greene WC, Robb RJ, Depper JM, Leonard WJ, Drogula C, Svetlik PB, Wong-Staal F, Gallo RC, Waldmann TA. Phorbol diester induces expression of Tac antigen on human acute T lymphocytic leukemic cells. Volume 133 of Issue 2. Journal of immunology (Baltimore, Md. : 1950) 1984. PMID: 6330200
Waldmann TA, Greene WC, Sarin PS, Saxinger C, Blayney DW, Blattner WA, Goldman CK, Bongiovanni K, Sharrow S, Depper JM. Functional and phenotypic comparison of human T cell leukemia/lymphoma virus positive adult T cell leukemia with human T cell leukemia/lymphoma virus negative Sézary leukemia, and their distinction using anti-Tac. Monoclonal antibody identifying the huma Volume 73 of Issue 6. The Journal of clinical investigation 1984. PMID: 6327770
Lipkowitz S, Greene WC, Rubin AL, Novogrodsky A, Stenzel KH. Expression of receptors for interleukin 2: Role in the commitment of T lymphocytes to proliferate. Volume 132 of Issue 1. Journal of immunology (Baltimore, Md. : 1950) 1984. PMID: 6418801
Leonard WJ, Depper JM, Waldmann TA, Greene WC. In: Greaves M (Ed.), Receptors and Recognition 1984. PMID:
Depper JM, Leonard WJ, Waldmann TA, Greene WC. In: Pick E (Ed.), Lymphokines 1984. PMID:
Waldmann TA, Broder S, Greene WC. In: Sasazuki T (Ed.), Immunogenetics: Its application to clinical medicine 1984. PMID:
Waldmann TA, Leonard WJ, Depper JM, Krönke M, Goldman CK, Oh T, Greene WC. Interleukin-2 receptor expression in retrovirus associated adult T-cell leukemia. Volume 15. 1984. PMID: 6100644
Waldmann TA, Goldman CK, Leonard WJ, Depper JM, Robb RJ, Korsmeyer SJ, Greene WC. Interleukin-2 receptors on activated malignant and normal B-cells. Volume 113. 1984. PMID: 6236954
Littman BH, Muchmore AV, Steinberg AD, Greene WC. Monoclonal lupus autoantibody secretion by human-human hybridomas. Selection of hybrids by conventional and novel techniques. Volume 72 of Issue 6. The Journal of clinical investigation 1983. PMID: 6605979
Leonard WJ, Depper JM, Robb RJ, Waldmann TA, Greene WC. Characterization of the human receptor for T-cell growth factor. Volume 80 of Issue 22. Proceedings of the National Academy of Sciences of the United States of America 1983. PMID: 6417659
Lando Z, Sarin P, Megson M, Greene WC, Waldman TA, Gallo RC, Broder S. Association of human T-cell leukaemia/lymphoma virus with the Tac antigen marker for the human T-cell growth factor receptor. Volume 305 of Issue 5936. 1983. PMID: 6195529
Robb RJ, Greene WC. Direct demonstration of the identity of T cell growth factor binding protein and the Tac antigen. Volume 158 of Issue 4. 1983. PMID: 6413637
Depper JM, Leonard WJ, Robb RJ, Waldmann TA, Greene WC. Blockade of the interleukin-2 receptor by anti-Tac antibody: inhibition of human lymphocyte activation. Volume 131 of Issue 2. Journal of immunology (Baltimore, Md. : 1950) 1983. PMID: 6408186
Korsmeyer SJ, Greene WC, Cossman J, Hsu SM, Jensen JP, Neckers LM, Marshall SL, Bakhshi A, Depper JM, Leonard WJ, Jaffe ES, Waldmann TA. Rearrangement and expression of immunoglobulin genes and expression of Tac antigen in hairy cell leukemia. Volume 80 of Issue 14. Proceedings of the National Academy of Sciences of the United States of America 1983. PMID: 6192435
Koretzky GA, Daniele RP, Greene WC, Nowell PC. Evidence for an interleukin-independent pathway for human lymphocyte activation. Volume 80 of Issue 11. Proceedings of the National Academy of Sciences of the United States of America 1983. PMID: 6407014
Cossman J, Neckers LM, Leonard WJ, Greene WC. Polymorphonuclear neutrophils express the common acute lymphoblastic leukemia antigen. Volume 157 of Issue 3. 1983. PMID: 6220104
Greene WC, Depper JM, Leonard WJ, Fleisher TA, Waldmann TA. Construction of human suppressor T cell hybridomas. Volume 2 of Issue 2. 1983. PMID: 6236341
Greene WC, Cossman J, Leonard WJ, Bakshi A, Waldmann TA, Korsmeyer SJ. In: Golde DW, Marks PA (Eds.), Normal and Neoplastic Hematopoiesis, UCLA Symposia on Molecular and Cellular Biology 1983. PMID:
Blaese RM, Tosato G, Greene WC, Fleisher TA, Muchmore AV. The role of cell surface lectin--carbohydrate interactions in cellular recognition, cooperation, and regulation. Volume 5 of Issue 2. 1983. PMID: 6193722
Leonard WJ, Depper JM, Uchiyama T, Smith KA, Waldmann TA, Greene WC. A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor. Volume 300 of Issue 5889. 1982. PMID: 6815536
Greene WC, Fleisher TA, Nelson DL, Waldmann TA. Production of human suppressor T cell hybridomas. Volume 129 of Issue 5. Journal of immunology (Baltimore, Md. : 1950) 1982. PMID: 6214585
Greene WC, Fleisher TA, Depper JM, Leonard WJ, Stanton GJ, Waldmann TA. Characterization of a soluble suppressor of human B cell function produced by a continuous human suppressor T cell line. II. Evidence for suppression through a direct action of CTC-SISS-B on human B cells. Volume 129 of Issue 3. Journal of immunology (Baltimore, Md. : 1950) 1982. PMID: 6213708
Fleisher TA, Attallah AM, Tosato G, Blaese RM, Greene WC. Interferon-mediated inhibition of human polyclonal immunoglobulin synthesis. Volume 129 of Issue 3. Journal of immunology (Baltimore, Md. : 1950) 1982. PMID: 6179992
Depper JM, Leonard WJ, Smith KA, Waldmann TA, Greene WC. In: Oppenheim JJ, Cohen S (Eds.), Interleukins, lymphokines, and cytokines 1982. PMID:
Greene WC, Goldman CK, Marshall ST, Fleisher TA, Waldmann TA. Stimulation of immunoglobulin biosynthesis in human B cells by wheat germ agglutinin. I. Evidence that WGA can produce both a positive and negative signal for activation of human lymphocytes. Volume 127 of Issue 2. Journal of immunology (Baltimore, Md. : 1950) 1981. PMID: 6265558
Fleisher TA, Greene WC, Uchiyama T, Goldman CK, Nelson DL, Blaese RM, Waldmann TA. Characterization of a soluble suppressor of human B cell immunoglobulin biosynthesis produced by a continuous human suppressor T cell line. Volume 154 of Issue 1. 1981. PMID: 6454754
Greene WC, Fleisher TA, Waldmann TA. Soluble suppressor supernatants elaborated by concanavalin A-activated human mononuclear cells. I. Characterization of a soluble suppressor T cell proliferation. Volume 126 of Issue 3. Journal of immunology (Baltimore, Md. : 1950) 1981. PMID: 6450803
Fleisher TA, Greene WC, Blaese RM, Waldmann TA. Soluble suppressor supernatants elaborated by concanavalin A-activated human mononuclear cells. II. Characterization of a soluble suppressor of B cell immunoglobulin production. Volume 126 of Issue 3. Journal of immunology (Baltimore, Md. : 1950) 1981. PMID: 6450804
Greene WC, Fleisher TA, Waldmann TA. Suppression of human T and B lymphocyte activation by Agaricus bisporus lectin. I. Suggestive evidence for a surface "suppressor" receptor in human lymphocytes. Volume 126 of Issue 2. Journal of immunology (Baltimore, Md. : 1950) 1981. PMID: 6778919
Greene WC, Waldmann TA. Inhibition of human lymphocyte proliferation by the nonmitogenic lectin wheat germ agglutinin. Volume 124 of Issue 6. Journal of immunology (Baltimore, Md. : 1950) 1980. PMID: 6966300
Parker CW, Greene WC. In: Cramer H, Schultz J (Eds.), Mechanism of Action 1977. PMID:
Parker CW, Greene WC, MacDonald HH. Cytochalasin binding in lymphocytes and polymorphonuclear leukocytes. Volume 103 of Issue 1. 1976. PMID: 991953
Greene WC, Parker CM, Parker CW. Cytochalasin sensitive structures and lymphocyte activation. Volume 103 of Issue 1. 1976. PMID: 186286
Greene WC, Parker CM, Parker CW. Colchicine-sensitive structures and lymphocyte activation. Volume 117 of Issue 3. Journal of immunology (Baltimore, Md. : 1950) 1976. PMID: 956646
Greene WC, Parker CM, Parker CW. Opposing effects of mitogenic and nonmitogenic lectins on lymphocyte activation. Evidence that wheat germ agglutinin produces a negative signal. Volume 251 of Issue 13. The Journal of biological chemistry 1976. PMID: 932019
Greene WC, Parker CM, Parker CW. Calcium and lymphocyte activation. Volume 25 of Issue 1. 1976. PMID: 183895
Atkinson JP, Greene WC, McNearney TA, Parker CW. Studies on the stimulation of cAMP metabolism in human lymphocytes by latex polymers. Volume 99 of Issue 2. 1976. PMID: 178514
Greene WC, Wedner HJ, Parker CW. In: Eijsvoogel W, Roos D, Zeijlemaker WP (Eds.), Leukocyte membrane determinants regulating immune reactivity 1976. PMID:
Parker CW, Dankner RE, Falkenhein SF, Greene WC. Suggestive evidence for both stimulatory and inhibitory domains on human lymphocytes, as indicated by phospholipid turnover studies with wheat germ agglutinin and other lectins. Volume 5 of Issue 1-2. 1976. PMID: 181319
Greene WC, Parker CW. A role for cytochalasin-sensitive proteins in the regulation of calcium transport in activated human lymphocytes. Volume 65 of Issue 2. Biochemical and biophysical research communications 1975. PMID: 167774
Sullivan TJ, Greene WC, Parker CW. Concanavalin A-induced histamine release from normal rat mast cells. Volume 115 of Issue 1. Journal of immunology (Baltimore, Md. : 1950) 1975. PMID: 50352
Peterson DT, Greene WC, Reaven GM. Effect of experimental diabetes mellitus on kidney ribosomal protein synthesis. Volume 20 of Issue 10. 1971. PMID: 5110696