Faculty ProfilesRima Arnaout, MD
555 Mission Bay Blvd South
San Francisco, CA 94158
Dr. Rima Arnaout is an Assistant Professor in Cardiology. She studies the genetic basis of heart development and disease at the Cardiovascular Research Institute, with a special interest in cardiomyopathy and arrhythmia. Working with Professor Shaun Coughlin, she uses zebrafish to study developmental gene function and to model human disease. She also studies heart disease using human genetics. Her clinical interests include general cardiology, cardiovascular genetics, and multi-modality imaging.
Cardiovascular Genetic and Genomics, Congenital Heart Disease, General Cardiology, Heart Development, Multi-modality Imaging, ZebrafishAwarded Grants
|Project Title||Project Number||Fiscal Year|
|Genetics and Structure of Trabecular Myocardium in Development and Disease||K08HL125945||2020|
|Genetic Analyst of Early Conduction System Development||F32HL110489||2013|
Orr N, Arnaout R, Gula LJ, Spears DA, Leong-Sit P, Li Q, Tarhuni W, Reischauer S, Chauhan VS, Borkovich M, Uppal S, Adler A, Coughlin SR, Stainier DY, Gollob MH. A mutation in the atrial-specific myosin light chain gene (MYL4) causes familial atrial fibrillation. Nat Commun. 2016; 7:11303.
Reischauer S, Arnaout R, Ramadass R, Stainier DY. Actin binding GFP allows 4D in vivo imaging of myofilament dynamics in the zebrafish heart and the identification of Erbb2 signaling as a remodeling factor of myofibril architecture. Circ Res. 2014 Oct 24; 115(10):845-56.
Chi NC, Shaw RM, Jungblut B, Huisken J, Ferrer T, Arnaout R, Scott I, Beis D, Xiao T, Baier H, Jan LY, Tristani-Firouzi M, Stainier DY. Genetic and physiologic dissection of the vertebrate cardiac conduction system. PLoS Biol. 2008 May 13; 6(5):e109.